Discipline: Nefrologie
De diensten Algemene kinder- en vaatheelkunde en Nefrologie en infectieziekten werken nauw samen aan een innovatieve vaattoegang voor hemodialyse
Hemodialyse zuivert het bloed door middel van een kunstnier. Een goede toegangsweg tot de bloedbaan is dan ook van levensbelang…
Orale anticoagulatie bij patiënten met voorkamerfibrillatie en ernstig nierlijden
Als men bij een patiënt voorkamerfibrillatie vaststelt en inschat dat de kans op een trombo-embolische beroerte groter is dan het…
Nobelprijswinnaar Sir Peter Ratcliffe gaf voordracht op Third International Renal Conference
Op 18 en 19 maart 2022 organiseerde de dienst Nefrologie en infectieziekten van campus Sint-Jan de ‘Third International Renal Conference’…
Zeven jaar hiv-referentiecentrum Brugge: tijd voor een terugblik
In 2014 kreeg het AZ Sint-Jan Brugge-Oostende AV de erkenning als hiv-referentiecentrum (HRC) voor de provincie West-Vlaanderen, een bekroning voor…
Multidisciplinaire benadering van primaire immuundeficiënties
Omdat de diagnostiek van primaire immuundeficiënties (PID) uitdagend is, werkte het AZ Sint-Jan Brugge-Oostende een multidisciplinaire benadering uit. Ze strekt…
Thuishemodialyse: een nieuwe behandelingsoptie voor patiënten met eindstadium nierfalen
Sinds eind 2018 kregen al verschillende patiënten op de dienst Nefrologie van het AZ Sint-Jan Brugge-Oostende AV een opleiding om…
De nefrologen en infectiologen houden hun kennis en kunde op topniveau
Vanuit de motivatie om kwalitatief hoogstaande geneeskunde volgens de recentste wetenschappelijke bevindingen aan te bieden, verfijnde elk van de zes…
Diabetes type 1 bij kinderen vraagt om een aanpak op maat
Door de toename van diabetes type 1 bij steeds jongere kinderen laat de nood zich voelen aan een gestructureerde, maar…
Succesvolle eerste editie van International Renal Conference
Chronische nierinsufficiëntie, een multidisciplinaire uitdaging
Nieuwe trends in de nierchirurgie
Medical mystery: hemoptoe en dyspneu
Nachtelijke dialyse verbetert levenskwaliteit van nierpatiënten
Publicaties
Noninvasive diagnosis of PLA2R-associated membranous nephropathy: a validation study.
Longevity and correlation with disease severity of the humoral and cellular response to SARS-CoV-2 infection in hemodialysis patients.
Predictors and dynamics of the humoral and cellular immune response to SARS-CoV-2 mRNA vaccines in hemodialysis patients: a multicenter observational study.
Trends in diagnosis, referral, red flag onset, patient profiles and natural outcome of de novo cardiac amyloidosis and their multidisciplinary implications.
Dynamics of the cellular and humoral immune response after BNT162b2 mRNA Covid-19 vaccination in Covid-19 naive nursing home residents.
Authors’ Reply.
Therapeutic trials in adult FSGS: lessons learned and the road forward.
Humoral and cellular immunogenicity and safety of the BNT162b2 mRNA Covid-19 Vaccine in nursing home residents.
Safety and efficacy of vitamin K antagonists versus rivaroxaban in hemodialysis patients with atrial fibrillation: a multicenter randomized controlled trial.
A target antigen-based approach to the classification of membranous nephropathy.
Anticoagulation management in hemodialysis patients with atrial fibrillation: evidence and opinion.
Incidence, characteristics and outcome of Covid-19 in adult patients on kidney replacement therapy: a region-wide cohort study.
PEXIVAS: The end of plasmapheresis for ANCA-associated vasculitis?
Effect of anti-interleukin drugs in patients with COVID-19 and signs of cytokine release syndrome (COV-AID): a factorial, randomised, controlled trial.
Dynamics of the cellular and humoral immune response after BNT162b2 mRNA Covid-19 vaccination in Covid-19 naive nursing home residents.
Humoral and cellular immunogenicity of the BNT162b2 mRNA Covid-19 Vaccine in nursing home residents.
Belgian Research on AIDS and HIV Consortium. Clinical haracteristics and outcomes of COVID-19 in people living with HIV in Belgium: A multicenter, retrospective cohort.
Incidence, risk factors, timing and outcome of influenza versus Covid-19 associated putative invasive aspergillosis.
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths.
X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19.
Dynamics of the cellular and humoral immune response after BNT162b2 mRNA Covid-19 vaccination in Covid-19 naive nursing home residents.
Predictors and Dynamics of the Humoral and Cellular Immune Response to SARS-CoV-2 mRNA Vaccines in Hemodialysis Patients: A Multicenter Observational Study.
Nocardia infections in hematopoietic cell transplant recipients: a multicenter international retrospective study of the Infectious Diseases Working Party (IDWP) of the European Society for Blood and Marrow Transplantation (EBMT).
COVID-19 infection in adult patients with hematological malignancies: a European Hematology Association Survey (EPICOVIDEHA).
Longevity and correlation with disease severity of the humoral and cellular response to SARS-CoV-2 infection in haemodialysis patients.
COVID-19-Associated Pulmonary Aspergillosis, March-August 2020.
Humoral and cellular immunogenicity of the BNT162b2 mRNA Covid-19 Vaccine in nursing home residents.
Hospital mortality in COVID-19 patients in Belgium treated with statins, ACE inhibitors and/or ARBs.
Incidence, risk factors, timing and outcome of influenza versus Covid-19 associated putative invasive aspergillosis.
Correction to: Sargramostim to treat patients with acute hypoxic respiratory failure due to COVID-19 (SARPAC): A structured summary of a study protocol for a randomised controlled trial.
Correction to: Treatment of severely ill COVID-19 patients with anti-interleukin drugs (COV-AID): A structured summary of a study protocol for a randomised controlled trial.
Sargramostim to treat patients with acute hypoxic respiratory failure due to COVID-19 (SARPAC): A structured summary of a study protocol for a randomised controlled trial.
Epidemiology of Pneumocystis jirovecii Pneumonia and (Non-)use of Prophylaxis.
Treatment of severely ill COVID-19 patients with anti-interleukin drugs (COV-AID): A structured summary of a study protocol for a randomised controlled trial.
Mycoplasma genitalium acquisition and macrolide resistance after initiation of HIV pre-exposure prophylaxis in men who have sex with men.
Incidence, characteristics and outcome of Covid-19 in adult patients on kidney replacement therapy: a region-wide cohort study.
The end of plasampheresis for ANCA-associated vasculitis?
Standardized Reporting of Monoclonal Immunoglobulin-Associated Renal Diseases: Recommendations from a Mayo Clinic/Renal Pathology Society Working Group.
In Reply to ‘Is SARS-CoV-2 Serology Relevant for Hemodialysis Patients With COVID-19?’
IgG Antibody Response to SARS-CoV-2 Infection and Viral RNA Persistence in Patients on Maintenance Hemodialysis.
Mycoplasma genitalium acquisition and macrolide resistance after initiation of HIV pre-exposure prophylaxis in men who have sex with men.
Prevention of nosocomial COVID-19: Another challenge of the pandemic.
Impact of solid cancer on in-hospital mortality overall and among different subgroups of patients with COVID-19: a nationwide, population-based analysis.
Low-dose hydroxychloroquine therapy and mortality in hospitalised patients with COVID-19: a nationwide observational study of 8075 participants.
Incidence, risk factors, timing and outcome of influenza versus Covid-19 associated putative invasive aspergillosis.
Comparison of four commercial SARS-CoV-2 IgG immuno-assays in RT-PCR negative patients with suspect CT findings.
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19.
Time between Symptom Onset, Hospitalisation and Recovery or Death: Statistical Analysis of Belgian COVID-19 Patients.
Successful Outcome of Disseminated Fusarium musae Fungemia with Skin Localization Treated with Liposomal Amphotericin B and Voriconazole in a Patient with Acute Myeloid Leukemia.
A case of a surgical-site infection with Staphylococcus condimenti.
Adrenal insufficiency, be aware of drug interactions!
Textiloma-Induced 1,25-Dihydroxyvitamin D-Mediated Hypercalcemia: A Case Report and Literature Study.
Other consequences from monoclonal immunoglobulins/fragments. Membranoproliferative glomerulonephritis and acquired Fanconi syndrome.
Membranoproliferative glomerulonephritis and cryoglobulinemic glomerulonephritis.
The approach to the patient with glomerular disease.
Membranous nephropathy.
Membranoproliferative glomerulonephritis.
Membranous nephropathy.
Glomerular diseases.
Indications to start kidney replacement therapy.
The peritoneal microcirculation in peritoneal dialysis.
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Factors influencing the progression of diabetic nephropathy.
Should we screen for coronary artery disease in asymptomatic chronic hemodialysis patients ?
Non-invasive diagnosis of primary membranous nephropathy using Phospholipase A2 receptor antibodies.
Evaluation of vitamin K status and rationale for vitamin K supplementation in dialysis patients.
Differentiating primary, genetic and secondary FSGS in adults: a clinicopathologic approach.
C3 glomerulopathy: Ten years’ experience at the Mayo Clinic.
A proposal for a serology-driven approach to membranous nephropathy.
Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference.
Fibromuscular dysplasia: results of a multicenter study in Flanders.
Proposal for Standardized Grading of Chronic Changes in Native Kidney Biopsy Specimens.
Complement activation in pauci-immune necrotizing and crescentic glomerulonephritis: Results of a proteomic analysis.
What are we missing in the clinical trials of focal segmental glomerulosclerosis?
Should statins be banned from dialysis?
Familial antiglomerular basement membrane disease in zero human leukocyte antigen mismatch siblings.
Interstitial immunostaining and renal outcomes in anti-neutrophil cytoplasmic antibody-associated glomerulonephritis.
The incidence of primary versus secondary focal and segmental glomerulosclerosis: a clinicopathological study.
C3 glomerulonephritis and autoimmune disease: more than a fortuitous association?
Mayo Clinic/ Renal Pathology Society Consensus Report on Pathologic Classification, Diagnosis, and Reporting of Glomerulonephritis.
Diagnosis of complement alternative pathway disorders.
The effects of vitamin K supplementation and vitamin K antagonists on progression of vascular calcification: ongoing randomized controlled trials.
The atrial fibrillation conundrum in dialysis patients.
Temporal IgG subtype changes in recurrent idiopathic membranous nephropathy.
Vitamin K antagonists for stroke prevention in hemodialysis patients with atrial fibrillation: a meta-analysis.
Hemodialysis catheter design and catheter performance: a randomized controlled trial.
Dose finding of rivaroxaban in hemodialysis patients.
High homocysteine induces betaine depletion.
C4d as a diagnostic tool in the diagnosis of proliferative glomerulonephritis.
Biomarkers in glomerular diseases: putting the cart before the wheel?
Opponent’s comments.
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In reply to “Hemodialysis catheters: which design is more cost-effective? And “Use of an uncensored primary outcome in a catheter design trial”.
Glomerular disease caused by dysregulation of the complement alternative pathway: an etiologic approach.
Measurement of pulse wave velocity, augmentation index and central pulse pressure in atrial fibrillation: a proof of concept study.
Global protein and histone arginine methylation are affected in a tissue-specific manner in a rat model of diet-induced hyperhomocysteinemia.
Protein-bound uremic toxins stimulate crosstalk between leukocytes and vessel wall.
Vitamin K2 Supplementation in Hemodialysis Patients: a Randomized Dosefinding Study.
Vancomycin: the tale of the vanquisher and the Pyrrhic victory.
A bone scan, no mistake!
The pharmacokinetics and pharmacodynamics of vancomycin in clinical practice: evidence and uncertainties.
Global protein and histone arginine methylation are affected in a tissue-specific manner in a rat model of diet-induced hyperhomocysteinemia.
Cystatin C versus creatinine for kidney function-based risk.
Reversion of cerebral artery stenoses due to tuberculomas with TNF-alpha antibodies.
Successful treatment of renal AA amyloidosis in familial Mediterranean fever with pegylated -2a interferon.
Vancomycin dosing in patients on intermittent hemodialysis.
Fluctuations of haemoglobinaemia in chronic hemodialysis patients.
Implementation of a dose calculator for vancomycin to achieve target through levels of 15-20 mg:ml in persons undergoing hemodialysis.
Diffuse alveolar bleeding caused by everolimus.
Recent changes in vancomycin use in renal failure.
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Comparison of the prognostic value of dipyridamole and dobutamine myocardial perfusion scintigraphy in end-stage renal disease.
Staphylococcus aureus infections in dialysis: what a nephrologist should know.
Guanidinocompounds after creatine supplementation in renal failure patients and their relation to inflammatory status.
Oral vitamin C administration increases lipid peroxidation in hemodialysis patients.
Autologous transplantation of bone marrow mononuclear cells for limb ischemia in a Caucasian population with atherosclerosis obliterans.
Author’s reply.
Diet-induced hyperhomocysteinemia does not lead to large gene expression differences in rat aorta.
Steroid-resistant sarcoidosis: is antagonism of TNF-α the answer ?
Decreased leukocyte recruitment in the mesenteric microcirculation of rats with cirrhosis is partially restored by treatment with peginterferon: An in vivo study.
Prevention of contrast-induced nephropathy: a critical review.
Renal side effects of anti-VEGF therapy in man: a new test system.
Novel insights in the treatment of diabetic nephropathy.
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A neutralizing VEGF antibody prevents glomerular hypertrophy in a model of obese type 2 diabetes, the Zucker diabetic fatty rat.
Activation of genes inducing cell-cycle arrest and of increased DNA repair in the hearts of rats with early streptozotocin-induced diabetes mellitus.
Linezolid-induced inhibition of mitochondrial protein synthesis.
What did we learn from animal models in peritoneal dialysis ?
Effects of peritoneal dialysis on the vascular bed of the peritoneal membrane.
RAGE-induced myofibroblast transdifferentiation of mesothelial cells contributes to peritoneal fibrosis in uremia.
Increased angiogenesis and permeability in the mesenteric microvasculature of rats with cirrhosis and portal hypertension: an in vivo study.
Current recommendations for diagnosis and management of polyoma BK virus nephropathy in renal transplant recipients.
Analytical and biochemical aspects associated with supraphysiological creatine intake.
Cytochrome P450-2C11 mRNA is not expressed in endothelial cells dissected from rat renal arterioles.
Inhibition of vascular endothelial growth factor (VEGF) does not affect early renal changes in a rat model of lean type 2 diabetes.
The John F. Maher recipient lecture 2004: RAGE in the peritoneum.
Animal models in peritoneal dialysis research: a need for consensus.
Benefits of switching from a conventional to a low-GDP bicarbonate/lactate-buffered peritoneal dialysis solution in a rat model.
Immunopathological changes in a uraemic rat model for peritoneal dialysis.
Pathophysiological role of vascular endothelial growth factor in the remnant kidney.
Management of therapy-resistant systemic lupus erythematosus with rituximab: report of a case and review of the literature.
Effects of new peritoneal dialysis solutions on leukocyte recruitment in the rat peritoneal membrane.
A case of secondary frosted branch angiitis in Behçet’s disease.
Creatine supplementation does not decrease total plasma homocysteine in chronic hemodialysis patients.
From hyperglycemia to diabetic kidney disease: the role of metabolic, hemodynamic, intracellular factors and growth factors/cytokines.
The role of hyperhomocysteinemia in relation to nitric oxide (NO) and endothelium-derived hyperpolarizing factor (EDHF)-mediated vasodilatation.
Long-term renal changes in the Goto-Kakizaki rat, a model of lean type 2 diabetes.
Vascular hyporesponsiveness in the mesenteric artery of anaesthetized rats with cirrhosis and portal hypertension: an in-vivo study.
Systemic and splanchnic haemodynamic effects of sildenafil in an in vivo animal model of cirrhosis: support for a risk in cirrhotic patients.
Endothelium-derived hyperpolarizing factor – mediated renal vasodilatory response is impaired during acute and chronic hyperhomocysteinemia.
The effects of peritoneal dialysate solutions on peritoneal host defense.
Prohepcidin accumulates in renal insufficiency.
The role of vascular endothelial growth factor in renal pathophysiology.
Long-term exposure to new peritoneal dialysis solutions: Effects on the peritoneal membrane.
The statement that folate supraphysiological levels in uremic patients do not cause harm should not go unchallenged.
Recent concepts in the molecular biology of the peritoneal membrane – Implications for more biocompatible dialysis solutions.
Prevention and treatment of acute renal failure in sepsis.
Renal angiomyolipoma in association with pulmonary lymphangioleiomyomatosis.
Effects of conventional and new peritoneal dialysis solutions on leukocyte recruitment in the microcirculation of the rat peritoneal membrane.
Extensive acronecrosis as a manifestation of mixed cryoglobulinemia.
Peritoneal microcirculation.
Inhibition of AGE-RAGE interaction prevents hyperglycemia-induced fibrosis of the peritoneal membrane.
The emerging role of VEGF in diabetic kidney disease.
Intravital videomicroscopy in peritoneal dialysis research.
Antibiotic administration in an animal model of chronic dialysate exposure.
Creatine-supplementation decreases homocysteine in an animal model of uremia.
Effect of dialyzer membrane pore size on plasma homocysteine levels in hemodialysis patients.
Pharmacologic treatment of acute renal failure in sepsis.
Prevention and nondialytic treatment of acute renal failure.
Effects of connexin-mimetic peptides on nitric oxide synthase- and cyclooxygenase-independent renal vasodilatation, basal renal blood flow and blood pressure.
Hemodynamic effects of conventional and new peritoneal dialysis solutions on the microcirculation of the rat peritoneal membrane. Role of acidity, buffer choice, glucose concentration and glucose degradation products.
Is folate a promising agent in the prevention and treatment of cardiovascular disease in patients with renal failure?
Why are homocysteine levels elevated in renal failure? A metabolic approach.
Experimental diabetes induces functional and structural changes in the peritoneum.
Compensatory glomerular hypertrophy following unilateral nephrectomy is strictly VEGF dependent.
Comparison of the radioiodinated serum albumin (RISA) dilution technique with direct volumetric measurements in animal models of peritoneal dialysis.
Amelioration of long-term renal changes in obese type 2 diabetic mice with a neutralizing vascular endothelial growth factor (VEGF)-antibody.
Molecular imaging of early events in the development of the diabetic cardiomyopathy.
Interesting news in peritoneal dialysis.
The effects of heparin administration in an animal model of chronic dialysate exposure.
Increased leukocyte rolling in newly formed mesenteric vessels in the rat peritoneal membrane during peritoneal dialysis.
Connexin-mimetic peptides: Influence on nitric oxide synthase- and cyclooxygenase-independent renal vasodilatation, basal renal blood flow and blood pressure in the rat.
Intravital microscopy: an integrated evaluation of peritoneal function and structure.
Antibodies against vascular endothelial growth factor improve early renal dysfunction in experimental diabetes.
Evidence-based treatment of hypertension in diabetes type 2.
Diabetes-induced renal microvascular dysfunction in the hydronephrotic kidney: role of nitric oxide.
Vascular endothelial growth factor is essential for hyperglycemia-induced structural and functional alterations of the peritoneal membrane.
Adsorption techniques and the use of sorbents.
Neoangiogenesis in the peritoneal membrane: does it play a role in ultrafiltration failure ?
Glucotoxicity of the peritoneal membrane: the case for VEGF.
Non anticoagulant effects of heparin: implications for animal models of peritoneal dialysis.
What happens to the peritoneal membrane in long-term peritoneal dialysis ?
Folate restores the NO synthase- and cyclooxygenase-resistant renal vasodilator response to acetylcholine in diabetes.
The role of dialyzer biocompatibility in acute renal failure.
Off-line analysis of red blood cell velocity in renal arterioles.
Endothelial dysfunction in diabetes.
The impaired renal vasodilator response attributed to endothelium-derived hyperpolarizing factor in streptozotocin-induced diabetic rats is restored by 5-methyltetrahydrofolate.
Acute renal failure in natural disasters.
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