Discipline: Neurologie
Het centrum voor cognitieve stoornissen: beperken van de impact van dementie door vroege detectie en interventie
Vlaanderen en het Brusselse Gewest tellen momenteel ongeveer 141.000 mensen met een of andere vorm van dementie. Tegen 2070 zal…
Nieuw, perfect uitgerust slaaplabo op campus Sint-Jan
Het slaaplabo op campus Sint-Jan verhuisde naar een ruimere locatie en is volledig vernieuwd. Het biedt patiënten alle comfort om…
NeuroSphereTM Virtual Clinic maakt consultatie en behandeling op afstand mogelijk na DBS-ingreep
Het Deep Brain Stimulation (DBS)-team op campus Sint-Jan biedt DBS-patiënten sinds begin mei 2022 in primeur voor België de mogelijkheid…
De succesfactoren van regionale beroertezorg
De toenemende technische complexiteit van het diagnostisch proces, de selectie van de optimale behandelstrategie en de hoge kwalitatieve eisen van…
Neuroloog, neurochirurg en algoloog bundelen krachten tegen trigeminusneuralgie
Trigeminusneuralgie (TN) is een invaliderend chronisch pijnsyndroom, gekenmerkt door spontane of uitgelokte aanvallen van een zeer hevige, schietende pijn in een zone van het gelaat.
Het vertigoteam houdt diverse disciplines in balans
Vertigo is een frequente klacht die vaak niet binnen één medische discipline thuis te brengen valt. Daarom koos campus Sint-Jan…
Repetitieve transcraniële magnetische hersenstimulatie bij moeilijk behandelbare depressie
Sinds 2007 werken de diensten Neurologie en Psychiatrie-psychosomatiek samen aan de realisatie van een aanvullend therapieaanbod voor patiënten met een…
Het DBS-centrum Brugge: de diensten Neurochirurgie en Neurologie in nauwe samenwerking
Vanuit een wens om de grote populatie van patiënten met bewegingsstoornissen de volledige waaier aan therapeutische mogelijkheden te kunnen aanbieden…
Erfelijke stofwisselingsziekten
De stofwisseling speelt een cruciale rol in het lichaam. Erfelijke aandoeningen kunnen stofwisselingsprocessen op zeer verschillende wijze verstoren. Hoewel de…
Het Neuromusculair Referentiecentrum biedt een medisch en paramedisch totaalzorgpakket
Neuromusculaire aandoeningen hebben een sterke impact op zowel de dagelijkse activiteiten als het sociale en familiale leven. Daarom, en ook vanwege hun zeldzame karakter, vereisen ze een multidisciplinaire medische en paramedische omkadering.
Nieuwe behandelingsmogelijkheden bij acute beroerte
Namens de leden van het Beroertezorgnetwerk Noord-West-Vlaanderen: dr. Sofie De Blauwe, dr. Danny Decoo, prof. Luc Defreyne, dr. Yvette Geerts,…
Doorgedreven parkinsonbegeleiding
De ziekte van Parkinson is onvoorspelbaar en veroorzaakt heel uiteenlopende beperkingen en obstakels. Genezing is vooralsnog niet aan de orde, maar de juiste medische en paramedische begeleiding kan de patiënt hulpmiddelen aanreiken om een optimale levenskwaliteit te verzekeren. Vandaar de oprichting van een gloednieuw parkinsonzorgprogramma in het AZ Sint-Jan Brugge-Oostende AV.
Hypothermie als behandeling voor acute ischemische beroerte
Elk jaar worden ongeveer 19.000 Belgen getroffen door een beroerte. In het merendeel van de gevallen gaat het om een ischemische beroerte. De morbiditeit, mortaliteit en het kostenplaatje zijn hoog. Naast de hemicraniëctomie op de “stroke unit” bij een maligne media-infarct en het toedienen van aspirine is de intraveneuze trombolyse een van de bewezen effectieve behandelingen in de acute fase. Helaas krijgt uiteindelijk slechts 5 tot 15% van alle patiënten intraveneus rtPA (recombinant weefselplasminogeenactivator) toegediend, gezien het beperkte tijdsvenster waarbinnen trombolyse kan worden toegepast: tot 4,5 uur na het ontstaan van de symptomen.
Medical mystery: abdominale klachten en krachtsvermindering (VIDEO)
Een 68-jarige man wordt opgenomen op de afdeling Maag-, Darm- en Leverziekten wegens verminderde eetlust, een opgezette buik, wisselende abdominale krampen en constipatie sinds een maand. ’s Ochtends ondervindt hij bovendien geregeld een veranderd “sponsachtig” gevoel ter hoogte van de buik. Bijkomend vermeldt hij een uitstralende pijn vanuit de heup naar de lies en later ook de lage rug. Sedert het begin van de klachten vermagerde hij een drietal kg en voelt hij zich vaak moe. Hij heeft geen koorts.
Botulinetoxine: een nieuwe aanwinst voor de behandeling van neurologische aandoeningen
Tijdens warme zomers zien we soms beelden in het nieuws van eenden met verlammingsverschijnselen: ze zijn ten prooi gevallen aan botulisme en kunnen niet meer vliegen. Warm zomerweer, waarbij vijvers droogvallen, creëert ideale omstandigheden voor de groei van Clostridium botulinum, de bacterie die het botulinetoxine produceert.
Bouwen aan expertise in slaaponderzoek
Slaapstoornissen zijn een frequent probleem met een belangrijke impact, en verdienen een geëigende en kwalitatieve aanpak. De vernieuwing van het slaaplabo in het AZ Sint-Jan Brugge-Oostende AV is slechts één van de nieuwe impulsen ter bevordering van een optimale diagnostiek en behandeling.
Nieuwe DNR-code voor AZ Sint-Jan Brugge Oostende AV
Een Do Not Reanimate (DNR) code is een communicatiemiddel tussen artsen dat urgent geconsulteerde dokters toelaat snel een gefundeerde beslissing te nemen. Andere namen zijn NTBR (Not To Be Reanimated), DNAR (Do Not Attempt Resuscitation) of NTR (Niet Te Reanimeren).
Medical mystery: intrauteriene groeiretardatie
Bij een zwangere dame bemerkt de gynaecoloog een belangrijke intrauteriene groeiretardatie. Antenatale echografie kan geen definitief uitsluitsel geven over de ernst en het type van placentaire abnormaliteit die wordt vermoed.
Multidisciplinaire training voor neglect
In april van dit jaar zijn we op de eenheid voor beroertezorg gestart met een nieuwe vorm van formele neglecttraining.…
Repetitieve transcraniële magnetische stimulatie (rTMS)
Neurologie werd lang beschouwd als een domein met beperkte therapeutische mogelijkheden. De laatste jaren is dit sterk geëvolueerd. Nieuwe medicijnen…
Diagnostische aanpak van patiënten met Mild Cognitive Impairment – Rol van de multidisciplinaire geheugenkliniek
Steeds meer patiënten worden verwezen voor diagnostiek en behandeling van lichte geheugenklachten. Hoewel de meeste patiënten met Mild Cognitive Impairment (MCI) een gunstige evolutie vertonen, ontwikkelt zich bij een significant aantal (18% per jaar) een dementie,doorgaans van het Alzheimertype (AD). Bovendien toont post mortemonderzoek bij MCIpatiënten vaak pathologische kenmerken van AD, zoals neurofibrillaire tangles in de hippocampus en entorhinale cortex.
Pilootproject voor de opvang van PVS- en MRS-patiënten
Door een ernstig hersenletsel kan een patiënt in een vegetatieve toestand terechtkomen. In 2004 ging een pilootproject van start dat gespecialiseerde opvang van deze patiënten voorziet. De dienst Neurologie van het AZ Sint-Jan AV neemt als een van de 14 Belgische expertisecentra deel aan het project.
Publicaties
Smoldering lesions in MS: if you like it then you should put a rim on it.
Neuroradiology. 2022 Apr;64(4):703-714. doi: 10.1007/s00234-021-02800-0. Epub 2021 Sep 9.PMID: 34498108
Evaluation of Humoral and Cellular Responses in SARS-CoV-2 mRNA Vaccinated Immunocompromised Patients.
Front Immunol. 2022 Mar 22;13:858399. doi: 10.3389/fimmu.2022.858399. eCollection 2022.PMID: 35401575 Free PMC article.
Unreported Imaging of Selective Vestibular Nerve Atrophy on Magnetic Resonance Imaging.
Otol Neurotol. 2022 Sep 8. doi: 10.1097/MAO.0000000000003654. Online ahead of print.PMID: 36075091 No abstract available.
Patients carrying the mutation p.R406W in MAPT present with non-conforming phenotypic spectrum.
Brain. 2022 Sep 29:awac362. doi: 10.1093/brain/awac362. Online ahead of print. PMID: 36171642
Continuous theta burst stimulation for drug-resistant epilepsy.
Front Neurosci. 2022;16:885905.
Efficacy and Safety of Ticagrelor and Aspirin in Patients With Moderate Ischemic Stroke: An Exploratory Analysis of the THALES Randomized Clinical Trial.
JAMA neurology. 2021;78:1091-1098 (doi:10.1001/jamaneurol.2021.2440)
Ticagrelor Added to Aspirin in Acute Ischemic Stroke or Transient Ischemic Attack in Prevention of Disabling Stroke: A Randomized Clinical Trial.
JAMA neurology. 2020
Ticagrelor Added to Aspirin in Acute Nonsevere Ischemic Stroke or Transient Ischemic Attack of Atherosclerotic Origin.
Stroke; a journal of cerebral circulation. 2020;51:3504-3513 (doi:10.1161/STROKEAHA.120.032239)
Safety and efficacy of GABAA alpha5 antagonist S44819 in patients with ischaemic stroke: a multicentre, double-blind, randomised, placebo-controlled trial.
Lancet neurology. 2020;19:226-233 (doi:10.1016/S1474-4422(20)30004-1)
Restenosis and risk of stroke after stenting or endarterectomy for symptomatic carotid stenosis in the International Carotid Stenting Study (ICSS): secondary analysis of a randomised trial.
Lancet neurology. 2018;17:587-596 (doi:10.1016/S1474-4422(18)30195-9)
A new imaging technique to monitor disease activity in susac syndrome?
European Stroke Journal. 2018;3:3-204, p. 255
Multicenter, retrospective analysis of endovascular treatment (EVT) in nonagenarians with acute ischemic stroke (AIS): Eligibility, outcome and safety.
European Stroke Journal. 2018;3:3-204, p. 167
Multicenter study of a personalized, digital coaching program after stroke: design and rationale.
European Stroke Journal. 2017;2:98-476
Public Policy in ALD/MND Care: The Belgian Perspective.
Bookchapter in: Public Policy in ALS/MND Care. Blank RH, Kurent JE, Oliver D (Eds). Palgrave Macmillan, Singapore. http://doi-org-443.webvpn.fjmu.edu.cn/10.1007/978-981-15-5840-5_3
Recently Diagnosed Early-Stage RRMS: NEDA, ARR, Disability Progression, Serum Neurofilament and Safety: 1-Year Interim Data From the Ocrelizumab Phase IIIb ENSEMBLE Study.
Neurology 2021;96:2261 (abstract).
Efficacité d’ocrelizumab (OCR) dans l’étude de phase IIIb ENSEMBLE : résultats intermédiaires à 1 an sur le taux d’absence d’activité de la maladie (NEDA avec IRM de rebaseline) dans la sclérose en plaques récurrente-rémittente (SEP-RR) à un stade précoce.
Revue Neurologique 2021;177:S106-7 (Abstract).
Two related cases of super-refractory status epilepticus due to 4-aminopyridine intoxication and an overview of the literature.
Epileptic Disorders 2021;23(3):527-30.
The care of people with ALS – the collaboration between neurology with palliative care across Europe.
Eur J Neurol 2021;28(S1):349 (Abstract).
TNN Neuro-imaging: Uw diagnose?
TNN 2021;122:351-3.
Contribution of homozygous and compound heterozygous missense mutations in VWA2 to Alzheimer’s disease. Neurobiol Aging.
2021 Mar;99:100.e17-100.e23. doi: 10.1016/j.neurobiolaging.2020.09.009. Epub 2020
Diagnostic Performance of Automated MRI Volumetry by icobrain dm for Alzheimer’s Disease in a Clinical Setting: A REMEMBER Study.
J Alzheimers Dis. 2021;83(2):623-639. doi: 10.3233/JAD-210450.
Signal quality as Achilles’ heel of graph theory in functional magnetic resonance imaging in multiple sclerosis.
Sci Rep. 2021 Apr 1;11(1):7376. doi: 10.1038/s41598-021-86792-0.PMID: 33795779 Free PMC article.
Alemtuzumab in multiple sclerosis: A retrospective analysis of occult hemorrhagic magnetic resonance imaging lesions and risk factors.
Eur J Neurol. 2021 Dec;28(12):4209-4213. doi: 10.1111/ene.15054. Epub 2021 Aug 20.PMID: 34374173
Smoldering lesions in MS: if you like it then you should put a rim on it.
Neuroradiology. 2021 Sep 9. doi: 10.1007/s00234-021-02800-0. Online ahead of print.PMID: 34498108
Neuropsychological outcome of amygdalohippocampal stimulation for refractory temporal lobe epilepsy.
58th AES Proceedings, Epilepsia 2004;45(suppl.7):150.
Efficacy and safety of amygdalohippocampal stimulation for refractory temporal lobe epilepsy.
58th AES Proceedings, Epilepsia 2004;45(suppl.7):185.
Deep brain stimulation for refractory temporal lobe epilepsy.
9th EFNS Proceedings, Eur J Neurol. 2005;12(s2):320.
Can mesenchymal-like stem differentiate towards neurons: the validity of neural gene expression as a proof for neural differentiation?
Acta Physiologica 2005;185(s649):O-6.
Deep brain stimulation for refractory temporal lobe epilepsy.
7th ECE Proceedings, Epilepsia 2006;47(suppl.3):5.
Low-dose whole brain γ-irradiation accelerates epileptogenesis during hippocampal kindling.
60st AES Proceedings, Epilepsia 2006;47(suppl.4):232-3.
Intracranial video-EEG monitoring at Ghent University Hospital.
7th ECE Proceedings, Epilepsia 2006;47(suppl.3):207.
Characterisation of the intrahippocampal kainic acid status epilepticus model using long-term video-EEG monitoring.
7th ECE Proceedings, Epilepsia 2006;47(suppl.3):75.
Measuring compound action potentials (CAPS) verifies vagus nerve stimulation (VNS) in rats.
11th EFNS Proceedings, Eur J Neurol. 2007;14(s1):93.
Adult-derived neural stem cells differentiate mainly towards astrocytes upon transplantation in the sclerotic hippocampus of a model for temporal lobe epilepsy.
37th Neuroscience Proceedings, 2007:778.29/E1.
Low dose, whole brain radiation suppresses hippocampal neurogenesis and accelerates kindling epileptogenesis.
Acta Physiologica 2007;191(s660):P-08.
An overview of 50 patients who underwent epilepsy surgery at Ghent University Hospital.
11th EFNS Proceedings, Eur J Neurol. 2007;14(s1):83.
Serial day rapid kindling is an effective tool in screening the anti-epileptic properties of topiramate.
1th EFNS Proceedings, Eur J Neurol. 2007;14(s1):208-9.
The effect of vagus nerve stimulation (VNS) on cortisol and ACTH in patients with refractory epilepsy.
61st AES Proceedings, Epilepsia 2007;48(suppl.6):275.
Vagus nerve stimulation induced changes in corticosterone in rats.
11th EFNS Proceedings, Eur J Neurol. 2007;14(s1):83.
Prospective screening of migraine criteria in Belgian patients with epilepsy.
11th EFNS Proceedings, Eur J Neurol. 2007;14(s1):79.
Invasive video-EEG monitoring at the reference center for refractory epilepsy at Ghent University Hospital: 15 years of experience.
11th EFNS Proceedings, Eur J Neurol. 2007;14(s1):82.
Correlation of interictal spikes and long-term efficacy in patients with refractory epilepsy treated with vagus nerve stimulation (VNS).
61st AES Proceedings, Epilepsia 2007;48(suppl.6):195-6.
Neural progenitor cells demonstrate long-term survival and differentiate mainly towards astrocytes upon transplantation in a sclerotic hippocampus.
11th EFNS Proceedings, Eur J Neurol. 2007;14(s1):315-6.
Vagus Nerve Compound Action Potentials (CAPs) verify Vagus Nerve Stimulation in rats.
Acta Physiologica 2008;192(s661):PO-10.
Efficacy of vagus nerve stimulation for refractory epilepsy among patient subgroups.
Acta Neurol Belg. 2008(suppl.):85.
Intrahippocampal delivery of adenosine reduces frequency of spontaneous seizures in the kainic acid rat model.
Acta Neurol Belg. 2008(suppl.):84.
Epilepsy surgery: diagnosis, techniques, outcome.
Epileptic Disord. 2008;10(4):382.
Invasive video-EEG monitoring, the experience at Ghent University Hospital.
Acta Physiologica 2008;192(s661):O-07.
Neuropsychological outcome of bilateral hippocampal stimulation for refractory temporal lobe epilepsy.
12th EFNS Proceedings, Eur J Neurol. 2008;15(s3):86-7.
Transplantation of neural progenitor cells in a sclerotic hippocampus give long term survival and differentiate mainly towards astrocytes.
Acta Physiologica 2008;192(s661):O-05.
Local delivery of adenosine has an anti-epileptic effect in rats with spontaneous seizures.
62nd AES Proceedings, Epilepsia 2008;49(suppl.7):382-3.
Hippocampal deep brain stimulation.
13th EFNS Proceedings, Eur J Neurol. 2009;16(s3):12.
Effect of hippocampal Deep Brain Stimulation on blood perfusion evaluated by µSPECT.
Acta Physiologica 2009;195(s670):P-12.
Local delivery and cell therapy for the treatment of refractory epilepsy.
13th EFNS Proceedings, Eur J Neurol. 2009;16(s3):13.
Effect of levetiracetam on hippocampal protein expression and cell proliferation in rats.
63rd AES Proceedings, Epilepsia 2009;50(s11):256.
Effect of levetiracetam on hippocampal protein expression and cell proliferation in rats.
Acta Physiologica 2009;197(s674):P-07.
Anti-epileptic effects of Vagus Nerve Stimulation in the focal pilocarpine model.
Acta Physiologica 2009;195(s670):P-10.
Identification of a brainstem evoked potential following cervical vagus nerve stimulation in rats.
8th ECE Proceedings, Epilepsia 2009;50(suppl.4):179.
In vivo measurements of vagus nerve compound action potentials in experimental rats.
63rd AES Proceedings, Epilepsia 2009;50(s11):346.
In vivo measurements of vagus nerve compound action potential in rats.
Acta Physiologica 2009;197(s674):P-05.
Beneficial effect of add-on levetiracetam in patients treated with vagus nerve stimulation for refractory epilepsy.
8th ECE Proceedings, Epilepsia 2009;50(suppl.4):195.
Local infusion of neuropeptide Y has anti-epileptic effects in fully kindled rats.
Acta Physiologica 2009;195(s670):P-11.
The identification of prognostic factors prior to invasive video-EEG monitoring.
8th ECE Proceedings, Epilepsia 2009;50(suppl.4):261.
Clinical added value of MEG in patients with refractory partial epilepsy and non-localizing conventional presurgical evaluation.
Acta Physiologica 2009;197(s674):O-01.
Local infusion of neuropeptide Y has anti-epileptic effects in fully kindled rats.
13th EFNS Proceedings, Eur J Neurol. 2009;16(s3):141.
Secretion of adenosine by foetal neural stem cells isolated from adenosine kinase deficient mice.
13th EFNS Proceedings, Eur J Neurol. 2009;16(s3):157.
Adenosine secretion by neural stem cells isolated from ADK-/- mice.
Acta Physiologica 2009;195(s670):P-13.
Prospective multicenter screening of migraine criteria in Belgian patients with epilepsy.
8th ECE Proceedings, Epilepsia 2009;50(suppl.4):159.
A novel implantable vagus nerve stimulation system (ADNS-300): pilot trial at Ghent University Hospital.
9th ECE Proceedings, Epilepsia 2010;51(s4):56.
The value of MEG in the presurgical evaluation of patients with refractory epilepsy.
14th EFNS Proceedings, Eur J Neurol. 2010;17(s3):50.
Memory performance after amygdalohippocampal deep brain stimulation in patients with medically refractory temporal lobe epilepsy.
29th IEC Proceedings, Epilepsia 2011;52(s6):227.
Lacosamide attenuates cortical excitability in the rat cortical stimulation model.
64rth AES Proceedings, Epilepsy Curr. 2011;11(s1):110.
ouse embryonic stem cell-derived pyramidal neurons are able to survive in a kainic acid cortical lesion and in a scleroritc hippocampus.
Acta Physiologica 2011;203(s687):PO-21.
Seven year follow-up in patients with refractory epilepsy treated with medial temporal lobe deep brain stimulation.
64rth AES Proceedings, Epilepsy Curr. 2011;11(s1):271.
Lacosamide attenuates cortical excitability in the rat cortical stimulation model.
Acta Physiologica 2011;203(s687):PO-22.
Mouse embryonic stem cell-derived pyramidal neurons are able to survive in a kainic acid cortical lesion and in a scleroritc hippocampus.
64rth AES Proceedings, Epilepsy Curr. 2011;11(s1):387.
Vagus nerve and hippocampal stimulation for refractory epilepsy.
In: ‘Seizure prediction in epilepsy: from basic mechanisms to clinical applications’ (Eds. Schelter B, Timmer J, Schulze-Bonhage A). Wilcey-VCH, 2008:283-98.
Consulted expert for the Chapter concerning ‘Guidelines for Headache’ (in the pharmacy).
Zelfzorgadvies in de apotheek, praktijkgids 2. Acco. Headache:pages 223-266.
Anévrismes chez des patients VIH-positifs.
Vaisseaux-Coeur-Poumons 2004;9(7):223-6.
Aneurysma’s bij HIV-positieve patiënten.
Bloedvaten-Hart-Longen 2004;9(7):223-6.
Anévrismes chez des patients VIH-positifs.
Neurone 2004;9(6):165-9.
Aneurysma’s bij HIV-positieve patiënten.
Neuron 2004;9(6):165-9.
Celtherapie voor neurologische aandoeningen: een beknopt overzicht.
Neuron 2006;11(1):19-26.
Studie over afwijkingen op de NMR-scan bij patiënten zonder een MS-opflakkering.
WOMS-info 2011;19:5-6.
Is er een link tussen het geven van borstvoeding en de kans op een nieuwe MS-opflakkering?
WOMS-info 2012;20:4-5.
Carotid artery aneurysm in human immunodeficiency virus infection.
Clin Neurol Neurosurg. 2005;107(5):404-7.
Cell therapy in models for temporal lobe epilepsy.
Seizure 2007;16(7):565-78.
Differentiation assays of bone marrow-derived Multipotent Adult Progenitor Cell (MAPC)-like cells towards neural cells cannot depend on morphology and a limited set of neural markers.
Exp Neurol. 2007;203(2):542-54.
Radiation of the rat brain suppresses seizure-induced neurogenesis and transiently enhances excitability during kindling acquisition.
Epilepsia 2007;48(10):1952-63.
Serial day rapid kindling is an effective tool in screening the anti-epileptic properties of topiramate.
Seizure 2007;16(7):620-6.
Deep brain stimulation in patients with refractory temporal lobe epilepsy.
Epilepsia 2007;48(8):1551-60.
Seizures in the intrahippocampal kainic acid epilepsy model: characterization using long-term video-EEG monitoring in the rat.
Acta Neurol Scand. 2009;119(5):293-303.
Unconditioned adult-derived neurosphere cells mainly differentiate towards astrocytes upon transplantation in sclerotic rat hippocampus.
Epilepsy Res. 2009;87(2-3):148-59.
Effect of levetiracetam on hippocampal protein expression and cell proliferation in rats.
Epilepsy Res. 2010;90(1-2):110-20.
A novel implantable vagus nerve stimulation system (ADNS-300) for combined stimulation and recording of the vagus nerve: pilot trial at Ghent University Hospital.
Epilepsy Res. 2010;92(2-3):231-9.
Evolution in VNS therapy for refractory epilepsy, experience with Demipulse devices at Ghent University Hospital.
Seizure 2010;19(9):531-5.
Predictive factors for outcome of invasive video-EEG monitoring and subsequent resective surgery in patients with refractory epilepsy.
Clin Neurol Neurosurg. 2010;112(2):118-26.
Deep brain and cerebellar stimulation for epilepsy (protocol).
Cochrane Database of Systematic Reviews 2010, Issue 4.
Quantitative analysis of adenosine using Liquid Chromatography/Atmospheric Pressure Chemical Ionization – tandem Mass Spectrometry (LC/APCI-MS/MS).
J Chromatogr B Analyt Technol Biomed Life Sci. 2010;878(19):1493-8.
Astrocytes derived from fetal neural progenitor cells as a novel source for therapeutic adenosine delivery.
Seizure 2010;19(7):390-6.
Continuous local intrahippocampal delivery of adenosine reduces seizure frequency in rats with spontaneous seizures.
Epilepsia 2010;51(9):1721-8.
The cognitive effects of amygdalohippocampal deep brain stimulation in patients with temporal lobe epilepsy.
Epilepsy Behav. 2011;22(4):759-64.
Local delivery strategies in epilepsy; a focus on adenosine.
Seizure 2011;20(5):376-82.
Spontaneous delayed brain herniation through a subdural membrane after tumor surgery.
J Neurol Surg A Cent Eur Neurosurg. 2013;74 Suppl 1:e25-9.
Sixth cranial nerve palsy in isolated sphenoid sinusitis: a case report.
Acta Neurol Belg. 2014;114(4):335-7.
Een overzicht van de nieuwe anti-epileptica.
Tijdschrift voor geneeskunde 2015;71(5):284-94.
A phase 3, long-term, open-label safety study of Galcanezumab in patients with migraine.
BMC Neurol. 2018;18(1):188.
Het calcitonine-gengerelateerde peptide als aangrijpingspunt voor nieuwe behandelingen van migraine.
Tijdschrift voor Geneeskunde. 2019;75(19):1132–41.
The Signaling Pathways Involved in the Anticonvulsive Effects of the Adenosine A1 Receptor.
Int. J. Mol. Sci. 2021;22(1), 320.
Journal scan ‘Nieuwe evidenced-based richtlijnen voor de behandeling van status epilepticus’.
Tijdschr. Neurol. Neurochir. 2021;122(2):85.
Medication overuse and drug addiction: a narrative review from addiction perspective.
J Headache Pain. 2021;22(1):32.
Two related cases of super-refractory status epilepticus due to 4-aminopyridine intoxication and an overview of the literature.
Epileptic Disord. 2021;23(3):527-530.
Accurate detection of typical absence seizures in adults and children using a two-channel electroencephalographic wearable behind the ears.
Epilepsia 2021;00:1–12.
CGRP monoclonal antibodies in migraine: an efficacy and tolerability comparison with standard prophylactic drugs.
J. Headache Pain 2021;22(1):128.
Case report rubriek Neuro-Imaging: uw diagnose?
eurol. Neurochir. 2021;122(7):351-3.
Nuclear oculomotor nerve paralysis.
Neuroophthalmology. 1987;7:219-222
Polyneuropathy in lithium intoxication.
Muscle Nerve. 1990;13:204-208 (doi:10.1002/mus.880130306)
Valproic acid and stupor.
Ned Tijdschr Geneeskd. 1991;135:191-192
Apraxia of eyelid opening secondary to right frontal infarction.
Acta neurologica Belgica. 1992;92:228-233
Crossed innervation of the superior rectus.
Clin Neurol Neurosurg. 1992;94:73-74 (doi:10.1016/0303-8467(92)90124-l)
Benign paroxysmal positional vertigo of the horizontal canal.
Journal of neurology, neurosurgery, and psychiatry. 1996;60:68-71 (doi:10.1136/jnnp.60.1.68)
Cerebral venous thrombosis and the G20210A mutation of factor II.
Stroke; a journal of cerebral circulation. 2000;31:543-544 (doi:10.1161/01.str.31.2.543)
Endarterectomy in carotid stenosis.
Minerva. 2000;3:109
Belgian Stroke C. Proposal of guidelines for stroke units.
Acta neurologica Belgica. 2002;102:49-52
EENHEID VOOR BEROERTEZORG: MULTIDISCIPLINAIRE ZORG-ORGANISATIE IN DE PRAKTIJK. DE ONTWIKKELING VAN EEN KLINISCH PAD & DE WERKING VAN DE WERKGROEP ACUTE BEROERTEZORG VAN HET NETWERK KLINISCHE PADEN.
Acta Hosp. 2002
Stroke Unit: Application of multidisciplinary organisation of patient care. Development of a clinical pathway and the study group of the network clinical pathways.
Acta Hosp. 2002:111
Stroke Unit: multidisciplinary cooperation in stroke care.
Tempo Medical. 2005:16
De behandeling van ischemische beroerte in de acute fase.
Neuron. 2005;10:20
Cerebrovasculaire aandoeningen [Cerebrovascular disease].
In: Kulbertus H, Van Mieghem W, eds. Atherosclerose and Atherothrombose [Atherosclerosis and Atherothrombosis]. Lubbeek: TransMed Medical Communications; 2006:340.
Chapter 8: Stroke in the Young.
In: Franke CL, Limburg M, eds. [Handbook - Cerebrovascular Diseases]. Utrecht: De Tijdstroom; 2006:471.
VITATOPS, the VITAmins TO prevent stroke trial: rationale and design of a randomised trial of B-vitamin therapy in patients with recent transient ischaemic attack or stroke (NCT00097669) (ISRCTN74743444).
Int J Stroke. 2007;2:144-150 (doi:10.1111/j.1747-4949.2007.00111.x)
Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study.
Lancet. 2007;369:275-282 (doi:10.1016/S0140-6736(07)60149-4)
Lessons from ONTARGET.
Acta clinica Belgica., et al. 2008;63:142-151 (doi:10.1179/acb.2008.025)
Multivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomized controlled trials: Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST).
Stroke; a journal of cerebral circulation. 2008;39:3316-3322 (doi:10.1161/STROKEAHA.107.510768)
Organisation of inhospital acute stroke care and minimum criteria for stroke care units. Recommendations of the Belgian Stroke Council.
Acta neurologica Belgica. 2009;109:247-251
Are ACE-inhibitors or ARB’s still needed for cardiovascular prevention in high risk patients? Insights from profess and transcend.
Acta clinica Belgica. 2010;65:107-114 (doi:10.1179/acb.2010.022)
The Belgian experience with intravenous thrombolysis for acute ischemic stroke.
Acta neurologica Belgica. 2010;110:157-162
Progressive multifocal leukoencephalopathy in liver transplant recipients: a case report and review of the literature.
Transplant international : official journal of the European Society for Organ Transplantation. 2011;24:e30-34 (doi:10.1111/j.1432-2277.2010.01190.x)
Stroke prevention in atrial fibrillation: current status and emerging therapies.
Acta cardiologica. 2012;67:161-167 (doi:10.1080/ac.67.2.2154206)
Reversion of cerebral artery stenoses due to tuberculomas with TNF-alpha antibodies.
Clin Neurol Neurosurg. 2012;114:1016-1018 (doi:10.1016/j.clineuro.2012.01.027)
Importance of proper patient selection and endpoint selection in evaluation of new therapies in acute stroke: further analysis of the SENTIS trial.
J Neurointerv Surg. 2013;5 Suppl 1:i21-24 (doi:10.1136/neurintsurg-2012-010562)
Tuberothalamic infarction causing a central Horner syndrome with contralateral ataxia and paraphasia.
Acta neurologica Belgica. 2015;115:727-729 (doi:10.1007/s13760-015-0490-4)
Time logistics and results of endovascular stroke treatment in a regional spoke-hub model.
European Stroke Journal. 2017;2:98-476 (doi:10.1177/2396987317705242)
Modified Rankin scale as a determinant of direct medical costs after stroke.
Int J Stroke. 2017;12:392-400 (doi:10.1177/1747493017691984)
An individualized coaching program for patients with acute ischemic stroke: Feasibility study.
Clin Neurol Neurosurg. 2017;154:89-93 (doi:10.1016/j.clineuro.2017.01.017)
White Paper on inequalities and unmet needs in the detection of atrial fibrillation (AF) and use of therapies to prevent AF‑related stroke in Europe.
IV Thrombolysis in stroke Mimics – Results from the sits international stroke thrombolysis register (sits-istr).
European Stroke Journal. 2018;3:3-204 (doi:10.1177/2396987318770127)
Personalized, digital coaching program after stroke (beroertecoach.be): preliminary results.
European Stroke Journal. 2018;3:3-204 (doi:10.1177/2396987318770127)
The combined impact of dependency on caregivers, disability, and coping strategy on quality of life after ischemic stroke.
Health Qual Life Outcomes. 2019;17:31 (doi:10.1186/s12955-018-1069-6)
Recommendations on telestroke in Europe.
Eur Stroke J. 2019;4:101-109 (doi:10.1177/2396987318806718)
Intravenous thrombolysis in stroke mimics: results from the SITS International Stroke Thrombolysis Register.
Eur J Neurol. 2019;26:1091-1097 (doi:10.1111/ene.13944)
Therapeutic hypothermia for acute ischaemic stroke. Results of a European multicentre, randomised, phase III clinical trial.
Eur Stroke J. 2019;4:254-262 (doi:10.1177/2396987319844690)
Thrombectomy is a cost-saving procedure up to 24 h after onset.
Acta neurologica Belgica. 2021 (doi:10.1007/s13760-021-01810-2)
Global Impact of COVID-19 on Stroke Care and IV Thrombolysis.
Neurology. 2021;96:e2824-e2838 (doi:10.1212/wnl.0000000000011885)
The impact of COVID-19 on acute stroke care in Belgium.
Acta neurologica Belgica. 2021;121:1251-1258 (doi:10.1007/s13760-021-01726-x)
Value of treatment by comprehensive stroke services for the reduction of critical gaps in acute stroke care in Europe.
Eur J Neurol. 2021;28:717-725 (doi:10.1111/ene.14583)
Cerebellar progressive multifocal leukoencephalopathy in a patient with a history of Crohn’s disease and acute myeloid leukemia.
Acta Neurol Belg 2020;120:759-60.
Kappa free light chains is a valid tool in the diagnostics of MS: a large multicenter study.
Mult Scler 2020;26:912-23.
Shorter infusion time of ocrelizumab: results from the randomized, double blind ENSEMBLE PLUS substudy in patients with relapsing-remitting multiple sclerosis.
Mult Scler Rel Dis 2020.
Late-onset Pompe disease (LOPD) in Belgium: clinical characteristics and outcome measures.
Orphanet J Rare Dis. 2020 Apr 5;15(1):83. doi: 10.1186/s13023-020-01353-4. PMID: 32248831; PMCID: PMC7133011.
Deciphering the Morphology of Motor Evoked Potentials.
Front Neuroinform. 2020 Jul 14;14:28. doi: 10.3389/fninf.2020.00028. eCollection 2020.
Stroke coach: a pilot study of a personal digital coaching program for patients after ischemic stroke.
Acta neurologica Belgica. 2020;120:91-97 (doi:10.1007/s13760-019-01218-z)
Multicenter, retrospective analysis of endovascular treatment for acute ischemic stroke in nonagenarians.
Journal of Stroke and Cerebrovascular Diseases. 2020;29 (doi:10.1016/j.jstrokecerebrovasdis.2020.104817)
Value of Treatment by Comprehensive Stroke Services for the reduction of critical gaps in acute stroke care in Europe.
European Journal of Neurology. 2020 (doi:10.1111/ene.14583)²
Recommendations on telestroke in Europe.
Zh Nevrol Psikhiatr Im S S Korsakova. 2020;120:33-41 (doi:10.17116/jnevro202012003233)
The relationship between Home-time, quality of life and costs after ischemic stroke: the impact of the need for mobility aids, home and car modifications on Home-time.
Disabil Rehabil. 2020;42:419-425 (doi:10.1080/09638288.2018.1501438)
Single MRI-Based Volumetric Assessment in Clinical Practice Is Associated With MS-Related Disability.
J Magn Reson Imaging. 2019 May;49(5):1312-1321. doi: 10.1002/jmri.26303. Epub 2018 Dec 31. PMID: 30597656
Fluoxetine in progressive multiple sclerosis: The FLUOX-PMS trial.
Mult Scler. 2019 Nov;25(13):1728-1735. doi: 10.1177/1352458519843051. Epub 2019 Jun 20. PMID: 31218911
There is an urgent need for palliative care specialists in MS – No.
Mult Scler. 2019 Nov;25(13):1712-1713. doi: 10.1177/1352458519855724. Epub 2019 Jul 25. No abstract available. PMID: 31343952
Single-arm study to assess comprehensive infusion guidance for the prevention and management of the infusion associated reactions (IARs) in relapsing-remitting multiple sclerosis (RRMS) patients treated with alemtuzumab (EMERALD).
Mult Scler Rel Dis 2019;29:7-14.
Kappa free light chains is a valid tool in the diagnostics of MS: a large multicenter study.
Multiple Sclerosis Journal 2019. Accepted for publication.
Intra-canal optic nerve cavernous haemangioma: a case report and review of the literature.
World Neurosurgery 2019;126:428-433.
Intensievezorgaspecten van het syndroom van Guillain-Barré in de 21ste eeuw: casusreeksen en systematische literatuurreview.
Tijdschr voor Geneeskunde 2019;75:
Neurosyfilis: de kameleon der psychiatrie. Literatuuroverzicht aan de hand van een casusbeschrijving.
Tijdschr Psychiatrie 2019;61:720-4.
There is an urgent need for palliative care specialists in MS. Controversies.
Multiple Sclerosis Journal 2019;25:1712-1713.
Assessment of opicinumab in acute optic neuritis using multifocal visual evoked potential.
CNS Drugs 2018;32:1159-71.
Loss of paraplegin drives spasticity rather than ataxia in SPG7: a European cohort analysis of 238 patients.
Targeting phosphocreatine metabolism in relapsing-remitting multiple sclerosis: evaluation with brain MRI, 1H and 31P MRS, and clinical and cognitive testing.
J Neurol. 2018 Sep 5.
Tubulinopathies continued: Refining the phenotypic spectrum associated with mutations in TUBG1.
Eur J Hum Genet. 2018 Aug;26(8):1132-1142. doi: 10.1038/s41431-018-0146-y. Epub 2018 Apr 30.
The natural history of Vanishing White Matter.
Ann Neurol. 2018 Aug;84(2):274-288. doi: 10.1002/ana.25287. Epub 2018 Sep 6.
Clinical variability and onset age modifiers in an extended Belgian GRN founder family.
Neurobiol Aging. 2018 Jul;67:84-94. doi: 10.1016/j.neurobiolaging.2018.03.007. Epub 2018 Mar 10.
A Belgian consensus protocol for autologous hematopoietic stem cell transplantation in multiple sclerosis.
Acta Neurol Belg. 2018 Jun;118(2):161-168. doi: 10.1007/s13760-018-0905-0. Epub 2018 Mar 13.
Rare nonsynonymous variants in SORT1 are associated with increased risk for frontotemporal dementia.
EU EOD Consortium. Neurobiol Aging. 2018 Jun;66:181.e3-181.e10. doi: 10.1016/j.neurobiolaging.2018.02.011. Epub 2018 Feb 17.
An intronic VNTR affects splicing of ABCA7 and increases risk of Alzheimer’s disease.
Acta Neuropathol. 2018 Jun;135(6):827-837. doi: 10.1007/s00401-018-1841-z. Epub 2018 Mar 27
No supportive evidence for TIA1 gene mutations in a European cohort of ALS-FTD spectrum patients.
EU EOD Consortium. Neurobiol Aging. 2018 Sep;69:293.e9-293.e11. doi: 10.1016/j.neurobiolaging.2018.05.005. Epub 2018 May 23.
Improving fatigue in multiple sclerosis by smartphone-supported energy management: The MS TeleCoach feasibility study.
Mult Scler Relat Disord. 2018 May;22:90-96. doi: 10.1016/j.msard.2018.03.020. Epub 2018 Mar 27.
Common and rare TBK1 variants in early-onset Alzheimer disease in a European cohort.
EU EOD Consortium. Neurobiol Aging. 2018 Feb;62:245.e1-245.e7. doi: 10.1016/j.neurobiolaging.2017.10.012. Epub 2017 Oct 25.
A Retrospective Belgian Multi-Center MRI Biomarker Study in Alzheimer’s Disease (REMEMBER).
J Alzheimers Dis. 2018;63(4):1509-1522. doi: 10.3233/JAD-171140.
NEK1 genetic variability in a Belgian cohort of ALS and ALS-FTD patients.
Neurobiology of Aging 2018(61):255e1-255e7.
Management of immune thrombocytopenia in multiple sclerosis patients treated with alemtuzumab treatment: a Belgian consensus.
Acta Neurol Belg 2018;118(1):7-11. Belgian Journal of Hematology 2018;9(3):118-23.
A Belgian Consensus Protocol for autologous hematopoietic stem cell transplantation in multiple sclerosis.
Acta Neurol Belg 2018;118(2):161-168.
The perils of late advance care planning in multiple sclerosis.
Bookchapter in: Case studies in neuropalliative care. Edited by Maisha T Robinson. Cambridge University Press 2018. ISBN 9781-108-40491-4.
Palliative Care in Multiple Sclerosis. Navigating chronic disease can be a difficult pill to swallow at a young age.
Bookchapter in: Case studies in neuropalliative care. Edited by Maisha T Robinson. Cambridge University Press 2018. ISBN 9781-108-40491-4.
Neo-adjuvant temozolomide bij inoperabel glioblastoom.
Tijdschr voor Geneeskunde 2018;74(7):493-501.
Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study.
The Lancet 2018: DOI: 10.1016/S0140-6736(18)30475-6
An intronic VNTR affects splicing of ABCA7 and increases risk of Alzheimer’s disease.
Acta Neuropathologica 2018;135(6):827-837.
Predictors of the response to opicinumab in acute optic neuritis.
Annals of Clinical and Translational Neurology 2018;5(10):1154-1162.
Multiple Sclerosis.
Neuropalliative Care: A Guide to Improving the Lives of Patients and Families Affected by Neurologic Disease. Springer 2018. ISBN 978-3-319-93214-9
Alzheimer’s disease and driving: review of the literature and consensus guideline from Belgian dementia experts and the Belgian road safety institute endorsed by the Belgian Medical Association.
Acta Neurol Belg. 2017 Dec;117(4):811-819. doi: 10.1007/s13760-017-0840-5. Epub 2017 Oct 5. Review.
A recurrent de novo mutation in TMEM106B causes hypomyelinating leukodystrophy.
Brain. 2017 Dec 1;140(12):3105-3111. doi: 10.1093/brain/awx314.
Pearls & Oy-sters: Visual agnosia: An overlooked cortical sign.
Neurology. 2016 Nov 8;87(19):e237-e238.
Fluoxetine in progressive multiple sclerosis (FLUOX-PMS): study protocol for a randomized controlled trial.
Trials 2014;15(1):37.
Phenotypic characteristics of Alzheimer patients carrying an ABCA7 mutation.
Neurology. 2016 Jun 7;86(23):2126-33. doi: 10.1212/WNL.0000000000002628.
Explorative genetic study of UBQLN2 and PFN1 in an extended Flanders-Belgian cohort of frontotemporal lobar degeneration patients.
Neurobiol Aging. 2013 Jun;34(6):1711.e1-5. DOI: 10.1016/j.neurobiolaging.2012.12.007
Clinical features of TBK1 carriers compared with C9orf72, GRN and non-mutation carriers in a Belgian cohort.
Brain. 2016 Feb;139(Pt 2):452-67. doi: 10.1093/brain/awv358
MRI with intrathecal gadolinium to detect a CSF leak: feasibility and long term safety from an open label single centre cohort study.
Neurology 2016;86(Supp P4.113). (abstract)
Wanneer Lemtrada bij multiple sclerose, een casus.
Neuron 2016; 21: 3.
Neurologie wordt een knelpuntberoep.
Artsenkrant 2016;2451:2.
Characterizing absolute lymphocyte count profiles in dimethyl fumarate–treated patients with MS.
Neurology: clinical practice 2016;6(3):220-229
Palliative Care in Multiple Sclerosis.
Continuum 2016; 22(3):943-946.
Loss of TBK1 is a frequent cause of frontotemporal dementia in a Belgian cohort.
Neurology. 2015 Dec 15;85(24):2116-25. doi: 10.1212/WNL.0000000000002220.
Rare Variants in PLD3 Do Not Affect Risk for Early-Onset Alzheimer Disease in a European Consortium Cohort.
Hum Mutat. 2015 Dec;36(12):1226-35. doi: 10.1002/humu.22908.
A 22-single nucleotide polymorphism Alzheimer’s disease risk score correlates with family history, onset age, and cerebrospinal fluid Aβ42.
Alzheimers Dement. 2015 Dec;11(12):1452-60. doi: 10.1016/j.jalz.2015.02.013.
Investigating the role of filamin C in Belgian patients with frontotemporal dementia linked to GRN deficiency in FTLD-TDP brains.
Acta Neuropathol Commun. 2015 Nov 10;3:68. doi: 10.1186/s40478-015-0246-7.
C9orf72 repeat size correlation with onset age of disease, hypermethylation and transcriptional downregulation of the C9orf72 promoter.
Mol Psychiatry. 2015 Oct 20. doi: 10.1038/mp.2015.159
A 62-Year-Old Woman with Muscle Weakness.
Clin Chem. 2015 Sep;61(9):1133-5. doi: 10.1373/clinchem.2014.227819.PMID: 26319449
Multiple nocardial abscesses of the brainstem and spinal cord: diagnosis after an open biopsy through a cervical partial central corporectomy.
Neurosurgery: Spine. 2015 Jun 19:1-4. [Epub ahead of print]
Bing-Neel Syndrome: two unexpected cases and review of the literature.
J Neurol Sci. 2015 Jun 16. pii: S0022-510X(15)00367-6. doi: 10.1016/j.jns.2015.06.026. [Epub ahead of print]
Clinical evidence for genetic anticipation in C9orf72 pedigrees.
Front. Neurosci. Published on 05 May 2015, doi:10.3389/conf.fnins.2015.89.00070
Ethics and End of Life in the Neuro-ICU.
Bookchapter in: Neurointensive Care: A Clinical Guide to Patient Safety.
Clinical utility and applicability of biomarker-based diagnostic criteria for Alzheimer’s disease: a BeDeCo survey.
Acta Neurologica Belgica 2015, jan 10
Predictive parameters for the effect of botulinum toxin infiltrations in chronic migraine.
Toxicon 2015, 93(Suppl):S9 (January 2015)
Safety and Tolerability of Anti-LINGO1 Monoclonal Antibody BIIB033 in Acute Optic Neuritis: The RENEW Trial.
Neurology 2015;84(14):Supplement P7.203 (abstract)
Evaluation of Comprehensive Alemtuzumab Infusion Guidance in Patients with Relapsing-remitting Multiple Sclerosis: EMERALD Study Design.
Neurology 2015;84(14):Supplement P7.283 (abstract)
Efficacy Analysis of the Anti-LINGO-1 Monoclonal Antibody BIIB033 in Acute Optic Neuritis: The RENEW Trial.
Neurology 2015;84(14):Supplement P7.202 (abstract)
Ethics and End of Life in the Neuro-ICU.
Bookchapter in: Neurointensive Care: A Clinical Guide to Patient Safety. K Shukri, A Wartenberg, T Abdelhak, Eds. Springer.
Palliative Care in Multiple Sclerosis.
Continuum 2015.
Palliatieve zorg in de neurologie: een barrière-analyse.
Nederlands-Vlaams Tijdschrift voor Palliatieve Zorg 2015-14(1):87. (abstract)
An initial survey on neurological palliative care.
Eur J Neurol 2015;22(Suppl.1): 282. (abstract)
Predictive parameters for the effect of botulinum toxin infiltrations in chronic migraine.
The Journal of Headache and Pain 2014, 15 (Suppl 1):M1 (18 September 2014)
Botulinum toxin infiltrations for chronic migraine are efficacious and safe: the Bruges experience.
Belgian Brain Council 2014 MODULATING THE BRAIN: FACTS, FICTION, FUTURE.
Autosomal recessive cerebellar ataxia of adult onset due to STUB1 mutations.
Neurology. 2014 May 13;82(19):1749-50. doi: 10.1212/WNL.0000000000000416. Epub 2014 Apr 9.
X-Linked Sideroblastic Anemia and Ataxia.
Seattle (WA): University of Washington, Seattle; 1993-2014.
Investigating the role of rare heterozygous TREM2 variants in Alzheimer’s disease and frontotemporal dementia.
Neurobiol Aging. 2014 Mar;35(3):726.e11-9. Epub 2013 Oct 9. DOI: 10.1016/j.neurobiolaging.2013.09.009.
Fluoxetine in progressive multiple sclerosis (FLUOX-PMS): study protocol for a randomized controlled trial.
Trials 2014;15(1):37.
Safety and efficacy of natalizumab in Belgian multiple sclerosis patients: subgroup analysis of the natalizumab observational program.
Acta Neurol Belg 2014.
Safety and efficacy of natalizumab in Belgian multiple sclerosis patients: subgroup analysis of the natalizumab observational program.
Acta Neurol Belg 2014;114(3):167-78.
Predictive parameters for the effect of botulinum toxin infiltrations in chronic migraine.
J Headache Pain 2014;15(1):1. (abstract
Are atraumatic spinal needles as efficient as traumatic needles for lumbar puncture?
Neurol Sci 2014;35(12):1997-9.
Investigating the role of rare heterozygous TREM2 variants in Alzheimer’s disease and frontotemporal dementia.
Neurobiol Aging. 2014 Mar;35(3):726.e11-9. Epub 2013 Oct 9
Pseudotumoral rebound of multiple sclerosis in a pregnant patient after stopping natalizumab
Multiple sclerosis and related disorders
Variant ataxia telangiectasia: clinical and molecular findings and evaluation of radiosensitive phenotypes in a patient and relatives.
Neuromolecular Med. 2013 Sep;15(3):447-57. doi: 10.1007/s12017-013-8231-4. Epub 2013 Apr 30.
Anti-glycine receptor antibody mediated progressive encephalomyelitis with rigidity and myoclonus associated with breast cancer.
Case Rep Neurol Med. 2013;2013:589154.doi:10.1155/2013/589154.
MRI characteristics of trigeminal nerve involvement in patients with multiple sclerosis
200-203
Phenotype and genotype in 101 males with X-linked creatine transporter deficiency.
J Med Genet. 2013 Jul;50(7):463-72. doi: 10.1136/jmedgenet-2013-101658. Epub 2013 May 3.
Explorative genetic study of UBQLN2 and PFN1 in an extended Flanders-Belgian cohort of frontotemporal lobar degeneration patients
34(6):1711.e1-5. doi: 10.1016/j.neurobiolaging.2012.12.007
Distinct clinical characteristics of C9orf72 expansion carriers compared with GRN, MAPT, and nonmutation carriers in a Flanders-Belgian FTLD cohort
70(3):365-73. doi: 10.1001/2013.jamaneurol.181
MRI characteristics of trigeminal nerve involvement in patients with multiple sclerosis.
Multiple Sclerosis and Related Disorders 2013;2(3):200-3.
Pseudotumoral rebound of multiple sclerosis in a pregnant patient after stopping natalizumab.
Multiple Sclerosis and Related Disorders 2013. http://www.msard-journal.com/article/S2211-0348(13)00117-X/abstract
Anti-Glycine receptor antibody mediated Progressive Encephalomyelitis with Rigidity and Myoclonus (PERM) associated with breast cancer.
Case Reports in Medicine 2013. http://dx.doi.org/10.1155/2013/589154
Thunderclap hoofdpijn als voornaamste symptoom van een acute ischemische beroerte.
Tijdschrift voor neurologie en neurochirurgie
Ischemic stroke presenting as thunderclap headache: a diagnostic pitfall.
E-poster European Stroke Conference London 2013
Botuline toxine: een nieuwe aanwinst in de behandeling van neurologische aandoeningen.
AZLink Juni 2012: 4-6
Intracranial hypertension following intrathecal administration of liposomal cytarabine.
J Neurol. 2011 Jan;258(1):162-3.
Defective membrane expression of the Na(+)-HCO(3)(-) cotransporter NBCe1 is associated with familial migraine.
Proc Natl Acad Sci U S A. 2010 Sep 7;107(36):15963-8
Neurons Generated from APP/APLP1/APLP2 Triple Knockout Embryonic Stem Cells Behave Normally In Vitro and In Vivo: Lack of Evidence for a Cell Autonomous Role of APP in Neuronal Differentiation.
Stem Cells 2010 Mar 31;28(3):399-406.
MicroRNA regulation of Alzheimer’s Amyloid precursor protein gene expression.
Neurobiol Dis. 2009 March; 33 (3): 422-428
Neuronal differentiation of murine embryonic stem cells.
Journal of Stem Cells, 2008, Volume 3, Issue 3
Opsoclonus-myoclonus syndrome: a clinicopathological confrontation.
Acta Neurol Belg. 2006 Sep;106(3):142-6
Clinical characteristics and long term prognosis in early onset multiple sclerosis.
J Neurol. 2006 Jun;253(6):720-3. Epub 2006 Mar 6.
Presentaties
Ethical aspects in dementia.
Continuous thetaburst stimulation for the treatment of refractory neocortical epilepsy.
alysis of Initial Non-response to Galcanezumab in Patients With Treatment-Resistant Migraine: Results From the CONQUER Trial.
N