Discipline: Laboratoriumgeneeskunde
Automatisering op maat in het 24-uurslabo op campus Sint-Jan
Op 16 februari 2022 nam de dienst Laboratoriumgeneeskunde op campus Sint-Jan een gloednieuw 24-uurslaboratorium in gebruik. EEN NIEUW HUIS Historisch…
De dienst Laboratoriumgeneeskunde gaat voor ‘samen sterker’
Campus Sint-Jan en campus Henri Serruys houden er voortaan één gemeenschappelijke dienst Laboratoriumgeneeskunde op na. Een fusie die de dienstverlening…
Overheidskader voor Next Generation Sequencing krijgt vorm
Het Next Generation Sequencing (NGS)-expertisenetwerk in het AZ Sint-Jan Brugge-Oostende AV is een feit. Dit opende de deur naar participatie…
Medical Mystery verhoogd MCV – Oplossing
Wat kan in deze casus een verklaring zijn voor de macrocytose? Het juiste antwoord: e. Hyperglycemie Alle antwoorden kunnen aanleiding…
Medical Mystery – Een onverwacht hoog MCV in de bloedresultaten
Bij opname op de spoedgevallendienst vertoont de bloedanalyse van een 55-jarige diabetes mellitus type 1-patiënt een onverwacht hoog MCV. Een 55-jarige man met diabetes mellitus…
Medical Mystery – Oplossing
CLL-patiënt met kaliumconcentratie van 10,1 mmol/L zonder klachten Dit is een geval van pseudo-hyperkaliëmie. In dit bijzondere geval adviseerde de…
Medical Mystery: CLL-patiënt met kaliumconcentratie van 10,1 mmol/L zonder klachten
Een paar jaar na de Richterse transformatie van haar chronisch lymfatische leukemie (CLL) tot een diffuus grootcellig lymfoom (DL-NHL) start…
Opsporing van Kingella kingae-DNA bij osteo-articulaire infecties bij kinderen
Bij kinderen komen osteo-articulaire infecties (OAI) zoals osteomyelitis, septische artritis en spondylodiscitis relatief weinig voor. Gezien een OAI tot ernstige…
Loopt jonge vijftiger verhoogd risico op vroegtijdig cardiovasculair lijden?
Het routineonderzoek van een 51-jarige roker classificeert deze in de categorie ‘matig risico’ op basis van een SCORE-berekening die lager…
Als eerste in Vlaanderen digitaal met orderaanvraagprocedure en transfusiemanagement
Van handhygiëne tot duidelijke en correcte communicatie, patiëntveiligheid is te allen tijde een topprioriteit binnen een ziekenhuis. Omdat onderzoek uitwees dat fouten in het labogebeuren voor 60% te wijten zijn aan misstappen in de preanalytische fase, digitaliseerde campus Henri Serruys als eerste ziekenhuis in Vlaanderen zowel zijn orderaanvraagprocedure als zijn transfusiemanagement.
Innovaties verruimen diagnostische mogelijkheden binnen de microbiologie
Dankzij de introductie van nieuwe moleculaire amplificatietechnieken en de MALDI-TOF massaspectrometer heeft de medische microbiologie de laatste jaren een enorme…
Dienst Laboratoriumgeneeskunde voortrekker in Europees cardiovasculair preventiebeleid
Op 25 en 26 september 2014 organiseerden de European Atherosclerosis Society (EAS) en de European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) hun eerste gemeenschappelijke symposium in het concertgebouw van Brugge, de “Atherosclerosis and Cardio-Endocrine Biomarkers Course”. Prof. dr. Michel Langlois trad op als voorzitter namens de Belgian Lipid Club en de dienst Laboratoriumgeneeskunde van het AZ Sint-Jan Brugge-Oostende AV. Internationale opinieleiders gaven er – voor een multidisciplinair publiek van endocrinologen, cardiologen, huisartsen, klinisch biologen en laboratoriumtechnologen – hun visie over nieuwe biomerkers voor het management van dyslipidemie en de preventie van atherosclerose en cardiovasculaire ziekte. Hierna volgt een verslag van enkele relevante presentaties voor de klinische praktijk.
Medical mystery: man met ademhalingsgebonden pijn, gewichtsverlies en nachtzweten
Een 35-jarige man komt op consultatie met ademhalingsgebonden pijn in het rechterhypochondrium. De pijn is er sinds een tweetal weken en straalt uit naar de rechterschouder. Bij navraag vermeldt de patiënt een gewichtsverlies van 17 kg op vier maanden tijd, hoewel hij zijn eetlust bewaarde, en ook nachtzweten zonder duidelijke koorts.
Evolutie van de prenatale screening naar aneuploïdie in het eerste trimester: van leeftijd tot NIPT
Twee à vier procent van alle pasgeborenen heeft een min of meer ernstige aangeboren misvorming. De huidige prenatale diagnostiek probeert…
Medical mystery: discrepant hoge TSH bij euthyreotische patiënt
Een 78-jarige man wordt naar de afdeling Endocrinologie doorverwezen wegens een vermoeden van langbestaande, niet-evolutieve subklinische hypothyreoïdie op basis van…
Respiratoire virologie – Wie zoekt, die vindt
Acute luchtweginfectie is het meest wijdverspreide type van acute infectie bij kinderen en volwassenen, en een significante oorzaak van ziekte bij immuungecompromitteerde patiënten. In 2002 waren respiratoire infecties verantwoordelijk voor 18% van de mortaliteit wereldwijd bij kinderen onder vijf jaar; diarree (15%) en malaria (11%) vormden de twee daaropvolgende belangrijkste oorzaken. Respiratoire infecties lokken niet enkel een toename van mortaliteit uit, maar veroorzaken eveneens een verhoogde morbiditeit in deze leeftijdsklasse.
Een snelle DNA-analyse voor de opsporing van foetale chromosoomafwijkingen
De triple en eerste trimester-screeningtesten, het uitgebreide echografische onderzoek en de leeftijd van de zwangere vrouw bepalen in sterke mate of er een verhoogd risico is op een numerieke chromosoomafwijking bij het ongeboren kind. Voor een snelle diagnose van de meest frequente foetale chromosoomafwijkingen werd recent een DNA-testmethode ontwikkeld, gebaseerd op de polymerase kettingreactie (PCR, Polymerase Chain Reaction).
Vitrificatie: Innovatieve invriestechniek met perspectieven
Succesvol invries-dooiprogramma in het Centrum voor Reproductieve Geneeskunde Brugge. Vandaag wordt zonder enige
twijfel aanvaard dat het invriezen van reproductieve cellen en embryo’s een noodzakelijke procedure is bij elke vooruitstrevende techniek in het domein van de reproductieve geneeskunde.
Nieuwe laboratoriumbenaderingen voor de preventie van cardiovasculaire morbiditeit en mortaliteit
Op 20 oktober 2007 vond in Brugge het Symposium van de Belgian Lipid Club (BLC) plaats, georganiseerd door dr. M. Langlois van het Laboratorium Klinische Scheikunde van AZ SintJan AV en Prof. V. Blaton. Naast enkele toonaangevende opinieleiders (Prof. P. Lansberg en Prof. J. Kastelein van het departement Vasculaire Geneeskunde van de Universiteit Amsterdam, Prof. G. De Backer van de Universiteit Gent en Prof. L. Van Gaal van de Universiteit Antwerpen) gaven zij er een presentatie over nieuwe benaderingenvoor de preventie van cardiovasculaire morbiditeit en mortaliteit.
Centrum voor Reproductieve Geneeskunde
Twintig jaar geleden ging het Centrum voor Reproductieve Geneeskunde (CRG) in AZ SintJan AV Brugge van start met IVFbehandelingen. Vandaag is het een van de 18 erkende Belgische B-centra(centrum met laboratorium en medisch begeleide voortplanting) en het enige Bcentrum in WestVlaanderen.
Kwaliteitscontrole: een label voor het Centrum Reproductieve Geneeskunde (CRG)
Sinds juni 2006 heeft de voormalige ‘Fertiliteitskliniek’ in AZ Sint-Jan AV Brugge een volledig nieuwe infrastructuur. Dat werd mee bereikt door de vruchtbare samenwerking met AZ Sint-Lucas te Brugge (Associatie B.I.R.T.H. – Bruges Institute for Reproductive Technology and Health), AZ Groeninge te Kortrijk (Associatie Centrum MBV West-Vlaanderen) en de satellietziekenhuizen uit de regio’s West- en OostVlaanderen. Het nieuwe ‘Centrum Reproductieve Geneeskunde’ (CRG) vindt u nu op de de tweede verdieping boven de Spoeddienst. Het CRG bestaat uit een polikliniek en een hiervan gescheiden, gesloten laboratorium. Dit laboratorium biedt alle technieken en procedures voor reproductieve geneeskunde, conform het aantal ingrepen en de actuele medisch-wetenschappelijke inzichten.
Innovatie in het lab toxicologie: TDM van immunosuppressiva met LC-MSMS
Therapeutische drug monitoring (TDM) van immunosuppressiva is essentieel om de farmacologische respons en het uiteindelijke resultaat van (orgaan)transplantaties te verbeteren. Bloedconcentraties moeten accuraat gemeten worden om een efficiënte en veilige therapie te garanderen, gezien de lage therapeutische index van de gebruikte geneesmiddelen (toxische/therapeutische dosis). Bovendien is er een risico op ernstige nevenwerkingen bij overdosering en transplantaatrejectie bij onderdosering.
Weefselbank AZ Sint-Jan AV bij FDA geregistreerd voor afname van hematopoiëtische stamcellen uit beenmerg en bloed
Onlangs behaalde de Bloedtransfusiedienst van het Laboratorium Hematologie van AZ Sint-Jan AV de ISO 9001- erkenning. Daarmee is ze de eerste Vlaamse bloedinstelling die een dergelijke erkenning geniet. Bovendien kreeg de Weefselbank een FDA-registratie voor de afname van hematopoiëtische stamcellen. Daarmee bewijst AZ Sint-Jan AV dat zij niet afwacht tot de overheid de zorgsector strengere kwaliteitsnormen oplegt maar haar patiënten en artsen nu al de beste kwaliteit biedt, vinden dr. Johan Billiet, dr. Arnold Criel en industrie-apotheker Dimitri Dehenau.
Baanbrekende acrosinetest voorspelt fertilisatiegraad
Bij routinesperma-analyse worden discrepanties vastgesteld tussen de acrosineactiviteit en de acrosomale morfologie van het sperma. Deze tegenstrijdige bevindingen werden aan AZ Sint-Jan AV geëvalueerd bij diagnostisch onderzoek van 107 infertiele echtparen geselecteerd voor in vitro fertilisatie (IVF). Uit deze studie bleek dat de acrosineactiviteit de fertilisatiegraad van het sperma kan voorspellen, en dit onafhankelijk van de morfologie van de spermacellen.
Publicaties
Chimerism monitoring using biallelic single nucleotide or insertion/deletion polymorphisms: how many markers to screen?
Clinica Chimica Acta 3 June 2022
Thouverin et al. PRECISION, the Belgian molecular profiling program of metastatic cancer for clinical decision and treatment assignment.
ESMO Open 2022 Aug:7(4):100524
Routine noninvasive prenatal screening for fetal rhesus D in maternal plasma – a two year experience from a single center in Belgium.
Transfusion 2022 May;62(5):1103-1109 PMID: 35352833
‘Comparative Assessment of Survival and Clinical Outcome Between Two Commercial Vitrification Kits with Different Warming Protocols After Blastocyst Culture: Potential Perspectives Toward Simplified Warming Procedures’.
https://link.springer.com/content/pdf/10.1007/s43032-023-01281-1.pdf
“Importance of anti-SARS-CoV-2 assay antigenic composition as revealed by the results of the Belgian external quality assessment (EQA) scheme”
Diagn Microbiol Infect Dis. 2021 Oct 11;102(2):115561. doi:10.1016/j.diagmicrobio.2021.115561. Online ahead of print.
“Re-emergence of enterovirus D68 in Europe after easing the COVID-19 lockdown, September 2021”
Euro Surveill. 2021 Nov;26(45). doi: 10.2807/1560-7917.ES.2021.26.45.2100998.
“Evaluation of the SARS-CoV-2 positivity ratio and upper respiratory tract viral load among asymptomatic individuals screened before hospitalization or surgery in Flanders, Belgium”
PlosOne. 2021 Nov 11;16(11):e0259908. doi: 10.1371/journal.pone.0259908
“Multicenter evaluation of the FilmArray Meningitis/Encephalitis assay in routine setting”
Journal of Medical Microbiology 2021. Accepted Sept 11. JMM-D-21-00276R1
“Acute SARS-CoV-2 Alpha variant infection leading to placental insufficiency and fetal distress”
J Med Virol. 2021 Oct 7. doi: 10.1002/jmv.27379.
“Predictors and dynamics of the humoral and cellular immune response to SARS-CoV-2 vaccination in hemodialysis patients: a multicenter observational study”
J Am Soc Nephrol. 2021 Sep 29: ASN.2021070908. doi:10.1681/ASN.2021070908.
“High prevalence of co-infecting enteropathogens in suspected rotavirus vaccine breakthrough cases”
J Clin Microbiol. 2021 Sep 29:JCM0123621.doi:10.1128/JCM.01236-21.
“Spotlight influenza: Extending influenza surveillance to detect non-influenza respiratory viruses of public health relevance: analysis of surveillance data, 2015-2019, Belgium”
Euro Surveill. 2021 Sep;26(38). doi: 10.2807/1560-7917.ES.2021.26.38.2001104.
“Multinational Observational Cohort Study of COVID-19-Associated Pulmonary Aspergillosis”
Emerg Infect Dis. 2021 Sep 14;27(11). doi: 10.3201/eid2711.211174.
“COVID-19 associated pulmonary aspergillosis: regional variation in incidence and diagnostic challenges.”
Intensive Care Med. 2021 Sep 1:1-2. doi: 10.1007/s00134-021-06510-2.
“Dynamics of the cellular and humoral immune response after BNT162b2 mRNA Covid-19 vaccination in Covid-19 naive nursing home residents”
J Infect Dis. 2021 Sep 13:jiab458.doi: 10.1093/infdis/jiab458. Online ahead of print.
“Mapping of serological testing and SARS-CoV-2 seroprevalence studies performed in 20 European countries, March-June 2020”
Journal of Global Health 2021 (J Glob Health 2021;11:05014) *representative of Belgium: M.Reynders
“Risk factors and outcome of pulmonary aspergillosis in critically ill coronavirus disease 2019 patients– a multinational observational study by the European Confederation of Medical Mycology”
Clin Microbiol Infect. 2021 Aug 25:S1198-743X(21)00474-2.doi:10.1016/j.cmi.2021.08.014. Online ahead of print.
“Longevity and correlation with disease severity of the humoral and cellular response to SARS-CoV-2 infection in haemodialysis patients”
Clinical Kidney Journal. 2021 Aug 13;14(11):2446-2448. doi:10.1093/ckj/sfab147. eCollection 2021 Nov.
“Comparison of 4 commercial enzyme immunoassays for serology testing of human parvovirus B19 infection”
Diagn Microbiol Infect Dis. 2021 Jul 16;101(3):115489. doi:10.1016/j.diagmicrobio.2021.115489.
“Diagnosis and treatment of COVID-19 associated pulmonary aspergillosis in critically ill patients: results from a European confederation of medical mycology registry”
Intensive Care Med. 2021 Jul 16 : 1–3. doi: 10.1007/s00134-021-06471-6
“Posaconazole for prevention of invasive pulmonary Aspergillosis in critically ill influenza patients (POSA-FLU): a randomised, open-label, proof-of-concept trial”
Intensive Care Med. 2021 Jun;47(6):674-686. doi: 10.1007/s00134-021-06431-0. Epub 2021 May 29.
“Pitfalls of rubella serology while on the brink of elimination: evaluation of national data, Belgium, 2017”
Euro Surveill. 2021 May ;26(20). doi: 10.2807/1560-7917.ES.2021.26.20.2000074.
“Humoral and cellular immunogenicity of the BNT162b2 mRNA Covid-19 Vaccine in nursing home residents”
Clin Infect Dis. 2021 Apr 7:ciab300. doi: 10.1093/cid/ciab300.
“Monitoring of human coronaviruses in Belgian ambulatories and hospitals in 2015-20: a surveillance study”
Lancet Microbe. 2021 Mar;2(3):e105-e114. doi: 10.1016/S2666-5247(20)30221-4. Epub 2021 Jan 27.
Infection prevention and control challenges in Flemish homecare nursing: a pilot study.
Br J Community Nurs. 2020 Mar 2;25(3):114-121. doi: 10.12968/bjcn.2020.25.3.114.PMID: 32160023
Multicenter study of automated systems for colistin susceptibility testing.
Eur J Clin Microbiol Infect Dis. 2021 Mar;40(3):575-579. doi: 10.1007/s10096-020-04059-4. Epub 2020 Oct 6.
Multicenter evaluation of the FilmArray Meningitis/Encephalitis assay in a routine setting.
Med Microbiol. 2021 Oct;70(10). doi: 10.1099/jmm.0.001438.PMID: 34665115
Performance assessment of the Devyser high-throughput sequencing based assay for chimerism monitoring in patients after allogeneic hematopoietic stem cell transplantation.
The Journal of Molecular Diagnostics Volume 23, Issue 9, September 2021, Pages 1116-1126
Uw diagnose?
Ned Tijdschr hematol 2021;18:93-5.
Efficacy of ruxolitinib in B-lymphoblastic leukaemia with PCM1-JAK2 fusion gene.
Br J Haematol. 2021 Feb;192(4):e112-e115. doi: 10.1111/bjh.17340. Epub 2021 Jan 27
The impact of Covic-19 pandemic on autoimmune diagnostics in Europe: a lesson to be learned.
Autoimmun Rev 2021, Oct 28:102985. doi: 10.1016/j.autrev.2021.102985. Online ahead of print.PMID: 34718167
Prevention of nosocomial COVID-19: Another challenge of the pandemic.
Infect Control Hosp Epidemiol. 2020 Apr 23 : 1–2. Published online 2020 Apr 23. doi: 10.1017/ice.2020.166
“Hepatitis E Virus Genotype 3 subtype dependent clinical outcomes in Belgium 2010-2018“.
Suppl. in Journal of Hepatology 73:S857 August 2020, doi:10.1016/S0168-8278(20)32157-7
“Successful Outcome of Disseminated Fusarium musae Fungemia with Skin Localization Treated with Liposomal Amphotericin B and Voriconazole in a Patient with Acute Myeloid Leukemia”.
Mycopathologia. 2020 Oct 29. doi: 10.1007/s11046-020-00499-w.
“Capturing Respiratory Syncytial Virus season in Belgium using influenza Severe Acute Respiratory Infection surveillance network (season 2018-2019)”.
Euro Surveill. 2020;25(39): pii=1900627. https://doi.org/10.2807/1560-7917. ES.2020.25.39.1900627
“Comparison of four commercial SARS-Cov-2 IgG immuno-assays in RT-PCR negative patients with suspect CT findings”.
Infection.2020 Sep 10:1-4. doi: 10.1007/s15010-020-01523-3.
“Incidence, risk factors, timing and outcome of influenza versus Covid-19 associated putative invasive aspergillosis.”
Infect Control Hosp Epidemiol. 2020 Sep 9:1-7. doi: 10.1017/ice.2020.460.
“In Reply to ‘Is SARS-CoV-2 Serology Relevant for Hemodialysis Patients With COVID-19?”
Am J Kidney Dis. 2020 Jun 27:S0272-6386(20)30783-6. doi:10.1053/j.ajkd.2020.06.005
“IgG Antibody Response to SARS-CoV-2 Infection and Viral RNA Persistence in Patients on Maintenance Hemodialysis “.
American Journal of Kidney Diseases. 2020 Jun 5:S0272-6386(20)30733-2. doi: 10.1053/j.ajkd.2020.05.009.
“Epidemiology of Pneumocystis jirovecii Pneumonia and (Non-)use of Prophylaxis”.
Front. Cell. Infect. Microbiol., 15 May 2020. https://doi.org/10.3389/fcimb.2020.00224
“Prevention of nosociomial Covid-19: another challenge of the pandemic”.
Infect Control Hosp Epidemiol. 2020 Apr 23:1-2. doi: 10.1017/ice.2020.166.
“Hepatitis E virus-associated hemophagocytic lymphohistiocytosis”.
Acta Clinica Belgica 2020 Feb 24:1-4. doi: 10.1080/17843286.2020.1733179.
“Evolution, geographic spreading, and demographic distribution of Enterovirus D68”.
BioRxiv, January 2020. doi: https://doi.org/10.1101/2020.01.10.901553
“What is the risk of missing legionellosis relying on urinary antigen testing solely? A retrospective Belgian multicenter study”.
Eur J Clin Microbiol Infect Dis. 2020 Apr;39(4):729-734. doi: 10.1007/s10096-019- 03785-8. Epub 2019 Dec 14.PMID: 31838606
“Prevalence and macrolide resistance of Mycoplasma genitalium after initiation of HIV preexposure prophylaxis”.
Sex Transm Infect. 2020 Jan 2. pii: sextrans-2019-054335. doi: 10.1136/sextrans-2019-054335.
Evaluation of Next Generation Sequencing based clonality analysis of T-cell receptor gamma gene rearrangements based on a new interpretation algorithm.
International Journal of Laboratory Hematology 2019;41(2):242-249.
Targeted next generation DNA sequencing for the detection of clonal haematopoiesis in idiopathic cytopaenia of undetermined significance (ICUS).
Belgian Journal of Hematology 2019;10:231-40
Spuriously high MCV in a patient with diabetic ketoacidosis.
Belgian Journal of Hematology 2019;10:250-4
Malignant progressionof Donor-engrafted Clonal hematopoiesis in sibling recipients after stem cell transplantation.
Blood Advances, Volume 4, Issue 22
The CCA Special Issue on Cardiovascular Markers.
Clin Chim Acta. 2020 [Editorial] doi: 10.1016/j.cca.2020.10.036
Update on current practice in laboratory medicine in respect of natriuretic peptide testing for heart failure diagnosis and management in Europe.
The CARdiac MArker Guideline Uptake in Europe (CARMAGUE) study. Clin Chim Acta 2020;511:59-66.
How well do laboratories adhere to recommended guidelines for dyslipidaemia management in Europe?
The CArdiac MARker Guideline Uptake in Europe (CAMARGUE) study. Chim Acta. 2020;508:267-272.
Non-HDL Cholesterol or apoB: Which to Prefer as a Target for the Prevention of Atherosclerotic Cardiovascular Disease?
Curr Cardiol Rep. 2020;22:67.
Quantifying atherogenic lipoproteins for lipid-lowering strategies: consensus-based recommendations from EAS and EFLM.
Atherosclerosis 2020;294:46-61.
Quantifying atherogenic lipoproteins for lipid-lowering strategies: consensus-based recommendations from EAS and EFLM.
Clin Chem Lab Med. 2020;58:496-517.
Evolving concepts on the management of dyslipidaemia.
Acta Clin Belg – Int J Clin Lab Med 2020;75:80-90.
Investigations on the clinical utility of apolipoprotein B measurement: A research priority.
Eur J Prev Cardiol. 2020;27:1252–1254 [Editorial].
Muscle strength is a major determinant of the blood pressure response to isometric stress testing: the Asklepios population study.
J Hypertens 2020;38:224-234.
“Serial detection of circulating Mucorales DNA in invasive mucormycosis: a retrospective multicentre evaluation”.
Journal of Fungi 2019. Accepted December 2019
“A Decade of Enterovirus Genetic Diversity in Belgium”.
J Clin Virol 2019. Oct 25;121:104205. doi: 10.1016/j.jcv.2019.104205.
“Human bocavirus infection in Belgian children with respiratory tract disease”.
Arch Virol. 2019 Sep 13. doi: 10.1007/s00705-019-04396-6.
“Toxoplasma gondii-Induced Brachial Plexus Neuropathy after Allogeneic Hematopoietic Stem Cell Transplantation”.
Transpl Infect Dis. 2019 Aug 8:e13157. doi: 10.1111/tid.13157.
“Lateral flow assays for diagnosing invasive pulmonary aspergillosis in adult hematology patients: a comparative multicenter study”.
Medical Mycology. 2019 Jul 9. doi: 10.1093/mmy/myz079
“Evaluation of the VIDAS hepatitis E IgM test in a nonendemic region”.
Diagn Microbiol Infect Dis. 2019. May 6. pii: S0732-8893(18)30567-4. doi: 10.1016/j.diagmicrobio.2019.04.012.
“Epidemiology and clinical impact of viral, atypical, and fungal respiratory pathogens in symptomatic immunocompromised patients: a two-center study using a multi-parameter customized respiratory Taqman® array card.”
Eur J Clin Microbiol Infect Dis. 2019 May 20. doi: 10.1007/s10096-019-03579-y
“The development and establishment of the 1st WHO BKV International Standard for nucleic acid based techniques”.
Biologicals. 2019 May 17 doi: 10.1016/j.biologicals.2019.04.004.
“A case of a surgical-site infection with Staphylococcus condimenti”.
“Oseltamivir for prophylaxis of influenza in vaccinated hemodialysis patients”
Infect Control Hosp Epidemiol. 2019 Apr;40(4):497-498. doi: 10.1017/ice.2019.11.
“Diagnosing invasive pulmonary aspergillosis in hematology patients: Retrospective multicenter evaluation of a novel lateral flow device”.
J Clin Microbiol. 2019 Mar 28;57(4). pii: e01913-18. doi: 10.1128/JCM.01913-18.
Evaluation of Next Generation Sequencing based clonality analysis of T-cell receptor gamma gene rearrangements based on a new interpretation algorithm.
International Journal of Laboratory Hematology 2019;41(2):242-249.
Targeted next generation DNA sequencing for the detection of clonal haematopoiesis in idiopathic cytopaenia of undetermined significance (ICUS).
Belgian Journal of Hematology 2019;10:231-40
Spuriously high MCV in a patient with diabetic ketoacidosis.
Belgian Journal of Hematology 2019;10:250-4
Diagnostic testing in myeloid malignancies by next-generation sequencing: recommendations from the Commission Personalised Medicine.
BELG J HAEMATOL 2019;10(6):241-9
Targeted next generation DNA sequencing for the detection of clonal haematopoiesis in idiopathic cytopaenia of undetermined significance (ICUS).
BELG J HAEMATOL 2019;10(6):231-40
Kappa Free Light Chains Is a Valid Tool in the Diagnostics of MS: A Large Multicenter Study.
Multiple Sclerosis Journal, 2019, DOI: 10.1177/1352458519845844
Bone marrow metastases from a 1p/19q co-deleted oligodendroglioma- a case report.
Quantifying atherogenic lipoproteins for lipid-lowering strategies: consensus-based recommendations from EAS and EFLM.
Atherosclerosis 2020 doi: 10.1016/j.atherosclerosis.2019.12.005.
Quantifying atherogenic lipoproteins for lipid-lowering strategies: consensus-based recommendations from EAS and EFLM.
Clin Chem Lab Med. 2019 doi: 10.1515/cclm-2019-1253.
Evolving concepts on the management of dyslipidaemia.
Acta Clin Belg – Int J Clin Lab Med 2019 https://doi.org/10.1080/17843286.2019.1702823
Muscle strength is a major determinant of the blood pressure response to isometric stress testing: the Asklepios population study.
J Hypertens 2020;38:224-234.
Investigations on the clinical utility of apolipoprotein B measurement: A research priority.
Eur J Prev Cardiol. 2019 doi: 10.1177/2047487319869578
Evaluation of next-generation sequencing-based clonality analysis of T-cell receptor gamma gene rearrangements based on a new interpretation algorithm.
8.
Int J Lab Hematol. 2018 Dec 8.
“Disseminated Mycobacterium genavense Infection in an immuno-competent Adult: a case report.”
Clin Microbiol Infect. 2018 Dec;24(12):1355-1356. doi: 10.1016/j.cmi.2018.07.013. Epub 2018 Jul 21.
“Diagnostic Utility of the Lymphoid Screening Tube for Ogata Score Calculation in Patients with Peripheral Cytopenia”.
Hematology. 2018 Dec;24(1):166-172.
An unexpected Campylobacter fetus infection.
Infection. 2018 Oct;46(5):729-730. doi: 10.1007/s15010-018-1159-8.
Mediastinal Myeloid Sarcoma with TP53 Mutation Preceding Acute Myeloid Leukemia with a PICALM-MLLT10 Fusion.
Acta Haematol 2018;140:97–104
Evaluation of the CellaVision DM96 advanced RBC application for screening and follow-up of malaria infection.
Diagn Microbiol Infect Dis. 2018 Apr;90(4):253-256. doi: 10.1016/j.diagmicrobio.2017.12.002.
Evaluation of four hemoglobin separation analyzers for hemoglobinopathy diagnosis.
J Clin Lab Anal. 2018;32:e22224.
Leukocyte telomere length and diet in the apparently healthy, middle-aged Asklepios population.
Sci Rep. 2018;8:6540.
Quantifying Atherogenic Lipoproteins: Current and Future Challenges in the Era of Personalized Medicine and Very Low Concentrations of LDL Cholesterol. A Consensus Statement from EAS and EFLM.
Clin Chem. 2018;64:1006-1033.
The Role of Nutraceuticals in Statin Intolerant Patients.
J Am Coll Cardiol. 2018;72:96-118.
Which Lipids Should Be Analyzed for Diagnostic Workup and Follow-up of Patients with Hyperlipidemias?
Curr Cardiol Rep. 2018;20:88.
Overview of the current status of familial hypercholesterolaemia care in over 60 countries – The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC).
Atherosclerosis. 2018;277:234-255.
A Belgian consensus strategy to identify familial hypercholesterolaemia in the coronary care unit and its subsequent cascade screening and treatment: BEL-FaHST (The BELgium Familial Hypercholesterolaemia STrategy).
Atherosclerosis. 2018;277:369-376.
“Urogenital pathogens, associated with Trichomonas vaginalis, among pregnant women in Kilifi, Kenya: A nested case-control approach”
BMC Infectious Diseases - INFD-D-18-00197R3; 2018
“Viral co-infections involving influenza A: changes observed during the 2009 pandemic season.”
Infect Dis Diag Treat. 2018 IDDT-116. doi: 10.29011/IDDT-116. 100016
“Prevalence and distribution of HCV genotypes in Belgium from 2008 to 2015.”
PLoS ONE 2018;13(12): e0207584
Isolation of Communicable Diseases.
GUIDE TO INFECTION CONTROL IN THE HOSPITAL CHAPTER 7 - Ed Gonzalo Bearman 2018
International consensus on ANA patterns (ICAP): inbedding in het Nederlandse taalgebied.
Laboratoriumgeneeskunde 2018;3:17-26
Diagnostic thresholds for free light chains in multiple myeloma depend on the assay used.
Leukemia 2018; 32(8):1815-1818
Antigen excess detection by automated assays for free light chains.
Clin Chem Lab Med 2018; 56(9) e235-e238. doi: 10.1515/cclm-2017-0977
Analytical performance of the single well titer function of NOVA View: good enough to omit ANA IIF titer analysis?
Clin Chem Lab Med 2018; 56(11):258-261.
Evaluation of Four Hemoglobin Separation Analyzers for Hemoglobinopathy Diagnosis.
Journal of Clinical Lab Analysis 2018;32(1)
Revised 2017 international consensus on ANCA testing in small vessel vasculitis: support from an external quality assessment.
Ann Rheum Dis 2018 Sept 5; pii: annrheumdis-2018-214078. doi: 10.1136/annrheumdis-2018-214078. [Epub ahead of print]
Evaluation of the CellaVision DM96 Advanced RBC Application for screening and follow-up of malaria infection.
Diagnostic Microbiology and Infectious Disease 2018;90(4):253-256
Diagnostic utility of the lymphoid screening tube supplemented with CD34 for Ogata score calculation in patients with peripheral cytopenia.
Hematology 2018;24(1):166-172.
“A disseminated Mycoplasma hominis infection in a patient with an underlying defect in humoral immunity”.
Infection. 44(3):379-81.
First EAS – EFLM consensus guideline on non-fasting lipid testing and reporting.
IFCC e-newsletter May-June 2016;20-21.
Lipidentesten op niet-nuchtere bloedafnames.
Eur Heart J 2016 en Clin Chem 2016 namens de Europese EAS/EFLM expertgroep
“Lipiden en lipoproteïnen” In: Wegwijs in Laboratoriumdiagnose.
Uitgeverij Acco 2016 p. 273-92. ISBN 978-94-6292-305-8.
Why are clinical practice guidelines not followed?
Clin Chem Lab Med. 2016;54:1133-9.
Haptoglobin phenotype and Parkinson disease risk.
Parkinsonism Relat Disord. 2016;22:108-9.
“Analytical and clinical comparison of Elecsys Syphilis (Roche®) – Architect Syphilis TP and Reformulated Architect Syphilis TP (Abbott®) assay”
Diagnostic Microbiology and Infectious Diseases 2016; DMID-16-734R2
Evaluation of the Red Blood Cell Advanced Software Application on the DM96.
International Journal of Laboratory Hematology 2016, 38(4):366-74.
Fasting is not routinely required for determination of a lipid profile-a joint consensus statement from the European Atherosclerosis Society and European Federation of Clinical Chemistry and Laboratory Medicine.
Eur Heart J. 2016;37:1944-58
Fasting Is Not Required for Determination of a Lipid Profile: Clinical and Laboratory Implications Including Flagging at Desirable Concentration Cutpoints.
Clin Chem. 2016;62:930-46.
How Well Do Laboratories Adhere to Recommended Clinical Guidelines for the Management of Myocardial Infarction: The CARdiac MArker Guidelines Uptake in Europe Study (CARMAGUE).
.
Clin Chem. 2016;62:1264-71.
Could accreditation bodies facilitate the implementation of medical guidelines in laboratories?
Clin Chem Lab Med. 2016 [Epub ahead of print]
“Therapeutic drug monitoring of meropenem in necrotizing enterocolitis: a challenge”.
Case Reports in Infectious Diseases 2016; 2016: 6207487.
“Heads or tails: genotyping of Hepatitis C Virus concerning the 2k/1b circulating recombinant form”.
International Journal of Molecular Sciences (Int J Mol Sci) 2016, 17(9),1384; doi:10.3390/ijms17091384
“Mycoplasma hominis: more than just an innocent bystander”.
Journal of Antimicrobial Agents (J Antimicro). 2(2):114. doi:10.4172/2472-1212.1000114
Dose finding study of rivaroxaban in hemodialysis patients.
American Journal of Kidney Diseases 2015;66(1):91-8.
Evaluation of Schistocyte Analysis by a Novel Automated Digital Cell Morphology Application.
International Journal of Laboratory Hematology 2015;37(5):588-96
Analysis of Phenotype and Outcome in Essential Thrombocythemia with CALR and JAK2 mutations.
Haematologica 2015;100(7):893-7.
Acquired thrombin and FV inhibitors upon aortic bioprosthetic valve replacement.
Haemophilia. 2014 Jul;20(4):e354-6. doi: 10.1111/hae.12469.
Biclonal biphenotypic B-cell lymphocytosis: a CLL in disguise?
Belgian Journal of Hematology 2014;5(4):143-7
HDL-gerichte therapieën: behandeling van een risicofactor of make-up van een risicomerker?
ISBN 978-90-81054-26-3 Transmed Medical Communications 2013 pp. 29-46.
Serum amyloid A is independently related to apolipoprotein A-I but not to HDL-cholesterol in patients with angina pectoris Clin Biochem.
2013 [Epub ahead of print].
Genetic aspects of scurvy and the European famine of 1845-1848
Nutrients 2013; 5:3582-8.
Comparison of two immunoassays for measurement of faecal calprotectin in detection of Inflammatory Bowel Disease: (pre)-analytical and diagnostic performance characteristics.
Clin Chem Lab Med 2013 (in press).
Guideline from the European Atherosclerosis Society: clinical view on laboratory checklist and issues
Biochimica clinica 2013; 375(Suppl.):S36
Critical review of laboratory investigations in clinical practice guidelines: proposals for the description of investigation.
Clin Chem Lab Med. 2013; 51:1217-26.
Pseudonephritis is Associated With High Urinary Osmolality and High Specific Gravity in Adolescent Soccer Players.
Pediatr Exerc Sci. 2013; 25:360-9
Accuracy of three automated 25-hydroxyvitamin D assays in haemodialysis patients
Clin Chim Acta 2013; 415:255-60
Microparticle number or procoagulant activity are not upregulated in healthy elderly persons.
Thromb Res. 2012;129(1): 98-100
Is it time to apply genographics in medical diagnosis?
Acta Clin Belgica 2012;67:387-8.
Human plasma protein polymorphisms and the persistence of cultural diversity.
Proc Natl Acad Sci U S A. 2012;109(43):E2914.
How I treat dyslipidemia according to the cardiovascular risk profile?
Rev Med Liège 2012; 67:167-173.
A genome-wide association study identifies rs2000999 as a strong genetic determinant of circulating haptoglobin levels
PLoS ONE 2012;7:e32327
Postanalytical opportunities of lipid and lipoprotein testing:laboratory approaches for predicting and managing risk of cardiovascular disease
Clin Chem Lab Med (invited article) 2012; 50:1169–1181.
The haptoglobin phenotype influences the risk of cutaneous squamous cell carcinoma in kidney transplant patients
J Eur Acad Dermatol Venereol 2012; 26:566-71.
Partial versus complete factor VIII inhibition in a mouse model of venous thrombosis.
Thromb Res. 2012; 129(4): 514-9
The effect of air pollution on hemostasis
Hamostaseologie 2012; 32(1): 5-13
Microparticle number or procoagulant activity are not upregulated in healthy elderly persons
Thromb Res. 2012;129(1): 98-100
Circulating apoptotic endothelial cells and apoptotic endothelial microparticles independently predict the presence of cardiac allograft vasculopathy
60(4): 324-31
Hemostatic changes in young and old mice upon subchronic exposure to air pollution in an urban roadside tunnel
108(4): 756-68
Changed gene expression in brains of mice exposed to traffic in a highway tunnel.
24(10): 676-686
Antidote strategies to reverse anticoagulation with TB-402, a long-acting partial inhibitor of FVIII.
10(7): 1371-8.
Effect of ageing on the murine venous circulation
137(4): 537-46
Air pollution-associated procoagulant changes: role of circulating microvesicles.
J Thromb Haemost 2012;1 0(1): 96-106
Presentaties
Belang van moleculaire diagnostiek bij MDS en MPN.
Belang van Moleculaire Diagnostiek bij MDS en MPN.
Performance evaluation of routine noninvasive prenatal screening for fetal rhesus D in maternal plasma.
“PCR-based detection of azole resistance in A. fumigatus to improve patient outcome. A prospective multicenter study”
“Comparison between VirClia and Platelia galactomannan assay on BAL samples”
“Pulmonary aspergillosis in critically ill coronavirus disease 2019 patients– a multinational study”
“Importance of anti-SARS-CoV-2 assay antigenic composition as revealed by the results of the Belgian external quality assessment (EQA) scheme”
‘ICAP questionnaire: Current laboratory and clinical practices in reporting and interpreting ANA IIFA patterns.’
An international survey on methodological aspects of anti-nuclear antibody testing by indirect immunofluorescence analysis: current practices for method verification.
Feasibility of harmonization in automated ANA IFA testing: results of the Benelux Multicenter study 2019.
An international survey on methodological aspects of anti-nuclear antibody testing by indirect immunofluorescence analysis: current practices for internal quality control.
Analytical performance of novel serum free light chain assays.
Clinical Decision guidelines for monoclonal gammopathies require an assay specific approach.
Free light chain antigen excess detection in three polyclonal assays on four analytical platforms.
Infectiepreventie op de werkvloer in Covid tijden. Financiële impact van de Covid-crisis op de werking van het ziekenhuis.
Update Covid 19 Webinar AZ St Jan Brugge (deel infectiepreventie).
Webinar HABO vzw: “COVID-19 Labodiagnostiek: een overzicht van de meest courante testmethoden”.
Webinar AZ Sint-Jan Brugge-Oostende AV: COVID-19.
“Hepatitis E Virus Genotype 3 subtype dependent clinical outcomes in Belgium 2010-2018“.
Casuistiek flowcytometrie.
Comparative Evaluation of Automated Mechanical Tissue Dissociation for Flow Cytometric Analysis.
Challenging diagnostic assessment of germline RUNX1 variants in myeloid malignancies: a case report of a patient presenting with a novel RUNX1 variant.
Immunophenotypic and molecular features of cuplike morphology in AML.
Donor cell-derived acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation: molecular confirmation by next-generation sequencing.
Comparative evaluation of automated mechanical tissue dissociation for flow cytometric analysis.
CHALLENGING DIAGNOSTIC ASSESSMENT OF GERMLINE RUNX1 VARIANTS IN MYELOID MALIGNANCIES: A CASE REPORT OF A PATIENT PRESENTING WITH A NOVEL GERMLINE RUNX1 VARIANT.
Immunophenotypic and molecular phenotyping of cup-like morphology in AML.
Donor cell-derived acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation: molecular confirmation by next-generation sequencing.
Early relapse detection after allogeneic stem cell transplantation by chimerism analysis based on Next Generation Sequencing of insertion/deletion polymorphisms.
CASE REPORT: SPURIOUSLY HIGH VITAMIN A AND E LEVELS DUE TO HYPERLIPIDEMIA.
Lipid testing in 2020.
Sessie “Viral respiratory infections: diagnostic options & epidemiology”
“Application of multi-parameter screening for the diagnosis of infectious diseases”
AB-BeleidsSymposium: “Nieuwe anti-infectieuze therapie anno 2019” “Update over virale en fungale infecties: diagnostische testen”
“Non-influenza viruses associated with Severe Acute Respiratory Infections during influenza seasons 2015/2016 to 2017/2018, Belgium”
“Increased prevalence of macrolide-resistant Mycoplasma genitalium after initiation of HIV pre-exposure prophylaxis”
“RSV infection in hospitalized adults with severe acute respiratory infection during four influenza seasons in Belgium: prevalence, subtype distribution, risk factors and outcome”
“COMPARISON OF THE REALSTAR® QUANTITATIVE PCR KIT AND A LABORATORY DEVELOPED SEMI-QUANTITATIVE PCR FOR THE DETECTION OF PNEUMOCYSTIS JIROVECII IN RESPIRATORY SAMPLES”
“Epidemiology of Pneumocysits jirovecii pneumonia and (non-)use of prophylaxis in three tertiary care hospitals”.
“Evaluation of the Altona RealStar® Pneumocystis jirovecii PCR kit 1.0 for quantitative detection of Pneumocystis jirovecii in various sample types”.
“Enterovirus surveillance of 2018 reveals an upsurge of EV-D68 in Belgium”.
“Epidemiology of human respiratory syncytial virus circulating in Belgium between 2011 and 2019” -abstract ID 241.
“RUBELLA SEROLOGY IN BELGIUM: WHAT’S IN A NUMBER?”
“Viral Compartmentalization and Rapid Evolution of Drug-resistant Herpes Simplex Virus (HSV-1) Infection in a Hematopoietic Stem Cell Transplant (HSCT) Patient.
“Epidemiology and Clinical Impact of Respiratory Pathogens in Symptomatic Immunocompromised Patients: a Two-center Study using a Multi-parameter Customized Respiratory Taqman Array Card”.
“Evaluation of the FilmArray Meningitis/Encephalitis panel in routine setting: a Belgian multicenter study”.
“Diagnostic characteristics of the recently commercialized OLM AspLFD lateral flow device in hematology patients: a multicenter study”.
“Improving the diagnostic performance of the newly commercialized IMMY Aspergillus galactomannan lateral flow assay using digital readout”.
“Bordetella pertussis seroprevalence in Belgian adults aged 40-59 years, 2017”.
TTP: diagnose, behandeling en FU.
Digitale microscopie.
Digitale microscopie.
Anemie.
Vernieuwingen in de stamcelbank.
Plaats van mutatieanalyse bij donorselectie: 2 voorbeelden.
Celvrij DNA: nieuwe diagnostische mogelijkheden.
Clonal hematopoiesis.
Droplet Digital PCR Phasing (DROP-PHASE): A Novel Method for Straightforward Detection of BCR-ABL1 Compound Mutations in Tyrosine Kinase Inhibitors Resistant Chronic Myeloid Leukemia (CML) and Acute Lymphoblastic Leukemia (ALL).
Results from the LIME survey ANA methodology. Sciensano symposium. The importance of harmonization in ANA testing. Latest progress of harmonization initiatives.
14th Dresden symposium on autoantibodies. 5th International Consensus on ANA Pattern (ICAP) Workshop 4th International Autoantibody Standardization (IAS) Workshop.
Update on Dyslipidaemia Guidelines and the rationale of Cardiovascular Disease Biomarker.
“Hepatitis E virus-associated haemophagocytic lymphohistiocytosis“.
Chloordioxide en koper-zilver ionisatie in de strijd tegen Legionella, een ervaringsverslag.
“Application of multiparameter screening & Taqman Array Card for the diagnosis of infectious diseases”
Casuistiek
“Evaluation of Simplexa™ C. difficile Direct assay for rapid diagnosis of Clostridium difficile infection compared to a multi-parameter customized respiratory TaqMan® array card”.
“Circulating strains of Human respiratory syncytial virus in Belgium during seven consecutive respiratory seasons (2011-2018)”.
“Overzicht diagnostiek CZS infecties”.
Een handvol Neurotrope Virussen.
LOK: Rol van NGS in de diagnostiek en prognose van MDS.
“Incidence and Clinical Relevance of Human Bocavirus (HBoV) Infections in Pediatric Patients”.
“Evaluation of Alere™ i for rapid detection of RSV and influenza A&B compared to a multi-parameter customized respiratory TaqMan® array card”.
Rol van NGS in de diagnostiek en prognose van MDS.
“Update in diagnostiek van SOA’s met nadruk op syphilis & M.genitalium”.
GENE PANEL ANALYSIS BY NEXT GENERATION SEQUENCING FOR THE DETECTION OF CLONAL HAEMATOPOIESIS IN IDIOPATHIC CYTOPENIA OF UNDETERMINED SIGNIFICANCE (ICUS) AND MYELODYSPLASTIC SYNDROME (MDS).
Case report: regular plasmapheresis in hyperchylomicronemia.
Comparison between Spectra optia® CMNC and MNC protocol for autologous peripheral blood stem cell collections.
Ogata-score berekening adhv de Lymphoid Screening Tube (LST) in de diagnose van MDS.
Progress in antigen excess detection.
“Decentralized Universal Neonatal Cytomagalovirus screening in Ghent and Bruges, Belgium”
Diagnostic utility of the Lymphoid Screening Tube for Ogata score calculation in MDS investigation.
Trainee breakfast panel.
Antibioticagebruik in de thuiszorg vanuit economisch aspect.
Vergelijking HPLC toestellen voor screening hemoglobinopathieën.
Principes van hemostase in vitro.
“Microbiological tools for CNS infections” (“Microbiologie voor de neuroloog”).
Uitbraak van een multi-resistente Acinetobacter baumannii op Intensieve Zorgen. Antimicrobial resistance – AMR The difference we must make together.
Problematiek van multi-resistente bacteriën.
Validation of first trimester non-invasive fetal RhD genotyping for targeted antenatalo anti-D prophylaxis.
Evaluation of the CellaVision DM96 Advanced RBC Application for screening and follow-up of malaria infection.
Diagnostic utility of the Lymphoid Screening Tube for Ogata score calculation in MDS investigation.
Bloed en beenmerg bij MDS.
Total complement activity (CH50): evaluation of thermostability and comparison of 2 liposome based assays OPtilite The Binding Site versus Autokit Wako.
Analytical performance of the single well titer function of NOVA View: good enough to omit ANA IIF titer analysis?
“Diagnostic tools in meningo-encephalitis”
Urgenties in de laboratoriumhematologie.
“Versant HCV Genotype 2.0 assay (LiPA) misclassifies the circulating HCV recombinant RF1_2k/1b in genotype 2 patients”
“Viral Respiratory Tract infections in immunocompromised patients”
Evaluation of Four Hemoglobin A1c Instruments.
“Prospective study in Belgian children hospitalized with RSV related lower respiratory tract infections: characterization of viral and clinical symptoms kinetics confirms a correlation between RSV viral load and disease severity.”
“Dyslipidemia- New clinical concepts and diagnostic tools”
Evaluation of Four Hemoglobin A1c Instruments.
Evaluation of Four Hemoglobin A1c Instruments.
“Focus diagnostics Simplexa™ Flu A/B & RSV versus multi-parameter customized respiratory Taqman® Array Card in immunocompromised patients”
“Characterization of clinical and viral kinetics in children hospitalized with respiratory syncytial virus related lower respiratory tract infections”
“Non-fasting lipid profiles: implications for lipoprotein measurement and reporting”
“Etiology of community-acquired respiratory infection & New Diagnostic Methods in Viral RTI”
INVLOED VAN NOAC’s OP ROUTINE EN SPECIALE STOLLINGSTESTEN.
Monoclonale B-cellymfocytose.
Urgenties in de laboratoriumhematologie.
“Heads or tails: genotyping of Hepatitis C Virus concerning the 2k/1b recombinant”
“Versant HCV Genotype 2.0 assay (LiPA) misclassifies the circulating HCV recombinant RF1_2k/1b in genotype 2 patients”
The conundrum of hematocrit measurements on hematopoietic progenitor cell apheresis products: differences between cell counters.
Evaluation of the Red Blood Cell Advanced Software Application on the CellaVision DM96.
STANDARDIZATION OF MRD DETECTION IN CML BY USE OF A PEER GROUP CONVERSION FACTOR
“Haptoglobin genotype and risk markers of cardiovascular disease”
LOK Cardiologie Richtlijnen en valkuilen bij het management van dyslipidemie
Euromedlab IFCC-EFLM Congress
Comparison of two extraction devices for determination of faecal calprotectin on ImmunoCAP250
Serum amyloid A is independently related to apolipoprotein A-I but not to HDL-cholesterol in patients with angina pectoris
Accuracy of three automated 25-hydroxyvitamin D immunoassays compared to ID-XLC-MSMS in haemodialysis patients
Accuracy of three automated immunoassays compared to ID-XLC-MSMS for the measurement of 25-hydroxyvitamin D in haemodialysis patients