Discipline: Endocrinologie
Endocrinologie: een kaleidoscoop aan expertise
De dienst Endocrinologie van campus Sint-Jan richt zich op een wijde waaier van endocriene ziekten, van diabetes mellitus en schildklierziekten,…
Een stap dichter bij de artificiële pancreas door nieuwe ontwikkelingen in diabetestechnologie: (Hybrid) Closed Loop Technology
Nieuwe technologieën waarmee mensen hun bloedglucosewaarde kunnen meten en insuline kunnen toedienen, zitten in een stroomversnelling. De Diabeteskliniek van het…
Blijft schildklierkanker een zeldzame ziekte?
De incidentie van schildkliercarcinoom neemt toe. Er is een significante stijging van kleinere tumoren, gedreven door een ontwikkeling van de beeldvorming en de steeds hogere precisie daarvan. In een hechte samenwerking met externe artsen wil het multidisciplinair schildklierkankerzorgteam aangepaste expertise en richtlijngestuurde zorg bieden.
Continue Glucosemonitoring biedt nieuwe perspectieven voor strikte glycemiecontrole
Sinds 1 september 2014 is de afdeling Endocrinologie-Diabetologie van het AZ Sint-Jan Brugge-Oostende AV door het RIZIV erkend voor de…
Medical mystery: discrepant hoge TSH bij euthyreotische patiënt
Een 78-jarige man wordt naar de afdeling Endocrinologie doorverwezen wegens een vermoeden van langbestaande, niet-evolutieve subklinische hypothyreoïdie op basis van…
Medical mystery: verhoogde TSH-waarde
Een 28-jarige vrouw komt op de raadpleging Endocrinologie omwille van een verhoogde TSH-waarde (thyroïdstimulerend hormoon) bij een routinelaboratoriumonderzoek verricht door de huisarts. De patiënte vertoont geen symptomen van hypothyroïdie en de halspalpatie is normaal.
De IKED-studie: Een gestructureerd programma voor kwaliteitsevaluatie en -bevordering in de Belgische diabeteszorg
Sinds 1988 kunnen Belgische diabetescentra een revalidatieovereenkomst voor zelfregulatie bij diabetespatiënten afsluiten met het RIZIV. In het kader van deze…
Publicaties
Predictors of neonatal adiposity and associations by fetal sex in women with gestational diabetes mellitus and normal glucose tolerant women.
Acta Diabetologica, 2020 Nov 20.
The impact of androgen deprivation therapy on bone mineral density in men treated for paraphilic disorder: A retrospective cohort study.
Andrology. 2022; 10: 545– 550.
Fasting plasma glucose level to guide the need for an OGTT to screen for gestational diabetes mellitus.
Acta Diabetol. 2022 Mar;59(3):381-394. doi: 10.1007/s00592-021-01812-9. Epub 2021 Nov 1.PMID: 34725724
Use of thyroid hormones in hypothyroid and euthyroid patients: a THESIS* survey of Belgian specialists *THESIS: treatment of hypothyroidism in Europe by specialists: an international survey.
Thyroid Res. 2022 Mar 5;15(1):3. doi: 10.1186/s13044-022-00121-9.PMID: 35248144 Free PMC article.
Combining data to perform population-based observational studies: know your sources. The case of thyroid cancer in Belgium.
Arch Public Health. 2022 Mar 10;80(1):77. doi: 10.1186/s13690-022-00803-8.PMID: 35272702 Free PMC article.
TPO antibody status prior to first radioactive iodine therapy as a predictive parameter for hypothyroidism in Graves’ disease.
Eur Thyroid J. 2022 Jun 29;11(4):e220047. doi: 10.1530/ETJ-22-0047. Print 2022 Aug 1.PMID: 35687484 Free PMC article.
Higher Thyroid fT3-to-fT4 Ratio Is Associated with Gestational Diabetes Mellitus and Adverse Pregnancy Outcomes.
J Clin Med. 2022 Aug 26;11(17):5016. doi: 10.3390/jcm11175016.PMID: 36078946 Free PMC article.
Type 1 diabetes-related autoimmune antibodies in women with gestational diabetes mellitus and the long-term risk for glucose intolerance.
Front Endocrinol (Lausanne). 2022 Aug 24;13:973820. doi: 10.3389/fendo.2022.973820. eCollection 2022.PMID: 36093103 Free PMC article.
Low gestational weight gain in women with gestational diabetes is safe with better metabolic profile postpartum.
J Clin Endocrinol Metab. 2022 Oct 14:dgac599. doi: 10.1210/clinem/dgac599. PMID: 36228141
Retrospective real-life study on preoperative imaging for minimally invasive parathyroidectomy in primary hyperparathyroidism.
Sci Rep. 2022 Oct 19;12(1):17427. doi: 10.1038/s41598-022-18219-3.PMID: 36261462 Free PMC article.
Recombinant thyrotropin use in children and adolescents with differentiated thyroid cancer: a multicenter retrospective study.
J. Clin Endocrinol Metab.2009 Oct;94(10):3948-53 - PMID:19773393
Graves Disease With Thyroid-Stimulating Hormone Receptor-Blocking Autoantibodies During Pregnancy.
Ann Intern Med. 2020 Jun 2;172(11):767-769. doi: 10.7326/L19-0818. Epub 2020 Mar 24.
The Impact of Regional Variation in Clinical Practice on Thyroid Cancer Diagnosis: A National Population-Based Study.
Eur Thyroid J. 2020 Jan;9(1):32-39. doi: 10.1159/000504046. Epub 2019 Nov 21.
Estimating the risk of gestational diabetes mellitus based on the 2013 WHO criteria: a prediction model based on clinical and biochemical variables in early pregnancy.
Acta Diabetol. 2020 Jun;57(6):661-671. doi: 10.1007/s00592-019-01469-5. Epub 2020 Jan 8.
Prediction of Glucose Intolerance in Early Postpartum in Women with Gestational Diabetes Mellitus Based on the 2013 WHO Criteria.
J Clin Med. 2019 Mar 19;8(3). pii: E383. doi: 10.3390/jcm8030383.
Risk factor screening for gestational diabetes mellitus based on the 2013 WHO criteria.
Eur J Endocrinol. 2019 Jun 1;180(6):353-363. doi: 10.1530/EJE-19-0117. PMID: 31120231
Characteristics and pregnancy outcomes across gestational diabetes mellitus subtypes based on insulin resistance.
Diabetologia. 2019 Nov;62(11):2118-2128. doi: 10.1007/s00125-019-4961-7. Epub 2019 Jul 23. PMID: 31338546
Adrenal insufficiency, be aware of drug interactions!
Endocrinol Diabetes Metab Case Rep. 2019 Oct 3;2019. pii: EDM190062. doi: 10.1530/EDM-19-0062. PMID: 31581123 Free PMC Article
Textiloma-Induced 1,25-Dihydroxyvitamin D-Mediated Hypercalcemia: A Case Report and Literature Study.
J Endocr Soc. 2019 Aug 27;3(11):2158-2164. doi: 10.1210/js.2019-00206. eCollection 2019 Nov 1. PMID: 31687642 Free PMC Article
Evolution in the management of thyroid cancer: an observational study in two referral centres in Belgium.
Acta Clin Belg. 2018 Feb 12:1-5. doi: 10.1080/17843286.2018.1435478. [Epub ahead of print] PMID: 29431057
“White Thyroid” on Unenhanced Computed Tomography in Amiodarone-Induced Thyrotoxicosis Type 2.
Thyroid. 2018 Jun;28(6):769-772. doi: 10.1089/thy.2017.0651. Epub 2018 May 11. PMID:29631498
The Sensitivity and Specificity of the Glucose Challenge Test in a Universal Two-Step Screening Strategy for Gestational Diabetes Mellitus Using the 2013 World Health Organization Criteria.
Diabetes Care. 2018 Jul;41(7):e111-e112. doi: 10.2337/dc18-0556. Epub 2018 May 10. No abstract available. PMID:29748432
Harmonization of Serum Thyroid-Stimulating Hormone Measurements Paves the Way for the Adoption of a More Uniform Reference Interval.
Clin Chem. 2017 Jul;63(7):1248-1260. doi: 10.1373/clinchem.2016.269456. Epub 2017 May 18. PMID: 28522444
Standardization of Free Thyroxine Measurements Allows the Adoption of a More Uniform Reference Interval.
Clin Chem. 2017 Oct;63(10):1642-1652. doi: 10.1373/clinchem.2017.274407. Epub 2017 Jul 18. PMID: 28720678
Bone scan alterations in aromatase inhibitor-treated patients.
Clin Nucl Med. 2015 Jan;40(1):38-40. doi: 10.1097/RLU.0000000000000588. PMID: 25290288
A Progress Report of the IFCC Committee for Standardization of Thyroid Function Tests.
Eur Thyroid J. 2014 Jun;3(2):109-16. doi: 10.1159/000358270. Epub 2014 May 7. PMID: 25114874
A bone scan, no mistake!
J Clin Endocrinol Metab. 2014 Dec;99(12):4447-8. doi: 10.1210/jc.2014-2915. . PMID: 25250637
Regional variation in thyroid cancer incidence in Belgium is associated with variation in thyroid imaging and thyroid disease management.
J Clin Endocrinol Metab. 2013 Oct;98(10):4063-71. doi: 10.1210/jc.2013-1705
Methylation defect in imprinted genes detected in patients with an Albright’s hereditary osteodystrophy like phenotype and platelet Gs hypofunction.
PLoS One. 2012;7(6):e38579. doi: 10.1371/journal.pone.0038579.
Atypical neurofibromas in neurofibromatosis type 1 are premalignant tumors.
Genes Chromosomes Cancer. 2011 Dec;50(12):1021-32. doi: 10.1002/gcc.20921.
A new approach to imprinting mutation detection in GNAS by Sequenom EpiTYPER system.
Clin Chim Acta. 2010 Dec 14;411(23-24):2033-9 PMID: 20807523
Acute thyrotoxicosis after SCT.
Bone Marrow Transplant. 2009 Apr;43(8):663-4. Epub 2008 Nov 17. No abstract available. PMID: 19011663 [PubMed - indexed for MEDLINE] PMID: 17986280
A brown tumor after biliopancreatic diversion for severe obesity.
Endocr J. 2009 Apr;56(2):263-8. Epub 2008 Dec 27. Erratum in: Endocr J. 2009 Jun;56(3):534.
Spuriously high thyrotropin values due to anti-thyrotropin antibodies in adult patients.
Clin Chem Lab Med. 2009;47(5):604-6. PMID: 19397486
Is the management of thyroid nodules and differentiated thyroid cancer in accordance with recent consensus guidelines? – Results of a national survey.
Clin Endocrinol (Oxf). 2008 Apr;68(4):599-604.
A thyroid thriller: acute transient and symmetric goiter after fine-needle aspiration of a solitary thyroid nodule.
Thyroid. 2008 Jan;18(1):81-4. PMID: 18302522
Advances in the medical management of differentiated thyroid carcinoma and their impact on the surgical approach.
Acta Chir Belg. 2007 Jun;107(3):271-8. Review. PMID: 17685252
Prevalence and predictors of sexual dysfunction in patients with type 1 diabetes.
Diabetes Care. 2003 Feb;26(2):409-14.
Sexual dysfunction in women with type 1 diabetes: a controlled study.
Diabetes Care. 2002 Apr;25(4):672-7.
A 35-year-old man with gynecomastia as the first symptom of hyperthyroidism.
Ned Tijdschrift Geneeskd. 2002 Feb 2, 146(5):222-224
Riedel’s thyroiditis and retroperitoneal fibrosis in multifocal fibrosclerosis: positron emission tomographic findings.
Clin Nucl Med, 27 (6), 413-415, 2002
Clinical relevance of thyroid fluorodeoxyglucose-whole body positron emission tomography incidentaloma, a new phenomenon.
Journal of Clinical Endocrinology and Metabolism, 87:1517-1520, 2002
Diagnostic Fine Needle Aspiration cytology and Immunochemistry Analysis of a Primary Thyroid Lymphoma presenting as an Anatomical Emergency .
Thyroid, 12, 169-173, 2002
Muscle fibre membrane instability in a young boy with an insulinoma.
Clin Endocrinol (Oxf).2001 Oct;55(4):559-561
“Evidence-based” 131 I bepaling bij hyperthyreoidie: actualiteit of toekomst?.
Tijdschrift voor Geneeskunde, 57:875-882, 2001.
Daily follow-up of serum parathyroid hormone and calcium after surgery for primary hyperparathyroidism.
J. Otolaryngol. 1999, dec; 28(6):305-308
Cabergoline in the treatment of hyperprolactinemia: a study in 455 patients.
Journal of Clinical Endocrinology and Metabolism, 84:2518-2522, 1999
Hormonal and volumetric long term control of a growth hormone-releasing hormone-producing carcinoid tumor.
Journal of Clinical Endocrinology and Metabolism, 84:3162-3169, 1999.
Diagnosis and management of tumors of the adrenal gland.
Springer-Verlag, Berlin Heidelberg p. 157-168, 1999.
Occult ectopic ACTH secretion due to recurrent lung carcinoid: long term control of hypercortisolism by continuous subcutaneous infusion of octreotide.
Clinical Endocrinology, 49:541-546, 1998
Prosthetic valve endocarditis due to Listeria Monocytogenes.
A case report with review of the literature. Acta Clinica Belgica, 49:95-98, 1994.
Cytomegalovirus infection in immunocompetent adults.
The European Journal of Medicine, 1:424-436, 1992.
Body composition, volumetric and areal bone parameters in male-to-female transsexual persons.
Bone. 2008;43(6):1016-21.
2011 Karyotyping, Is It Worthwhile in Transsexualism?
J Sex Med. 2011;8(2):475-8.
Sexual desire in female-to-male transsexuals.
Eur J Endocrinol. 2011;165(2):331-7.
Quality of life and sexual health after sex reassignment surgery in female-to-male transsexuals.
J Sex Med. 2011;8(12):3379-88.
Reproductive wish in transsexual men.
Hum Reprod. 2012;27(2):483-7.
Long-Term Evaluation of Cross-Sex Hormone Treatment in Transsexual Persons.
J Sex Med. 2012;9(10):2641-51.
Bone Mass, Bone Geometry, and Body Composition in Female-to-Male Transsexual Persons after Long-Term Cross-Sex Hormonal Therapy.
J Clin Endocrinol Metab 2012 ;97(7):2503-11.
Bone size and bone strength are increased in obese male adolescents.
J Clin Endocrinol Metab. 2013;98(7):3019-28.
Transgenderism and reproduction.
Curr Opin Endocrinol Diabetes Obes. 2013;20(6):575-9.
Long-term evaluation of donor-site morbidity after radial forearm flap phalloplasty for transsexual men.
J Sex Med. 2013;10(6):1644-51.
Low bone mass is prevalent in male-to-female transsexual persons before start of cross-sex hormonal therapy and gonadectomy.
Bone 2013;54:92-97.
Short- and long-term clinical skin effects of testosterone treatment in trans men.
J Sex Med. 2014;11(1):222-9.
Associations of sex steroids with bone maturation, bone mineral density, bone geometry and body composition: a cross-sectional study in healthy male adolescents.
J Clin Endocrinol Metab. 2014 Jul;99(7):E1272-82.
Relation of adrenal steroids with bone maturation,- mineral density and -geometry in healthy prepubertal and early pubertal boys.
Bone. 2014 Dec;69:39-46.
Sex steroids in relation to sexual and skeletal maturation in obese male adolescents.
J Clin Endocrinol Metab. 2014 Aug;99(8):2977-85.
A critical evaluation of salivary testosterone as a method for the assessment of serum testosterone.
Steroids. 2014;Apr 30;86C:5-9. Steroids. 2014 Aug;86:5-9.
Cross-sex hormone therapy in trans persons is safe and effective at short-time follow-up: results from the European Network for the Investigation of Gender Incongruence.
J Sex Med. 2014 Aug;11(8):1999-2011.
Bone health in trans persons: clinical evaluation and relevance.
Okt 2014 (Phd thesis)
Prevalence of Gender Nonconformity in Flanders, Belgium.
Arch Sex Behav. 2015 Jul;44(5):1281-7.
Body composition, bone turnover and bone mass in trans men during testosterone treatment: one year follow-up data from a prospective case-controlled study (ENIGI)
Eur J Endocrinol. 2015 Feb;172(2):163-71.
Cross-sex hormone treatment in male-to-female transsexual persons reduces serum brain-derived neurotrophic factor (BDNF).
Eur Neuropsychopharmacol. 2015 Jan;25(1):95-9.
Preservation of bone mass in trans women during cross-sex hormonal therapy: a prospective observational study.
Osteoporos Int. 2015 Jan;26(1):35-47.
Bone in trans persons.
Curr Opin Endocrinol Diabetes Obes. 2015 Dec;22(6):459-66.
A European Network for the Investigation of Gender Incongruence: Endocrine Part.
J Sex Med. 2016 Jun;13(6):994-9.
Growth, sexual and bone development in a boy with bilateral anorchia under testosterone treatment guided by the development of his monozygotic twin.
J Pediatr Endocrinol Metab. 2018 Mar 28;31(3):361-367.
Prospective evaluation of hematocrit in gender-affirming hormone treatment: results from European Network for the Investigation of Gender Incongruence.
Andrology. 2018 May;6(3):446-454.
Proandrogenic and antiandrogenic progestins in transgender youth differential effects on body composition and bone metabolism.
.
J Clin Endocrinol Metab 103:2147-56.
Growth, sexual and bone development in a boy with bilateral anorchia under testosterone treatment guided by the development of his monozygotic twin.
J Pediatr Endocrinol Metab 31:361-67.
Pediatric reference values for tibial trabecular bone mineral density and bone geometry parameters using peripheral quantitative computed tomography.
Calcif Tissue Int 96:527-33.
Androgens and obesity in male adolescents.
Curr Opin Endocrinol Diabetes Obes 22:230-7.
Body composition, bone turnover and bone mass in trans men during testosterone treatment: 1 year follow-up data from a prospective case-controlled study.
Eur J Endocrinol 172:163-71.
Preservation of bone mass in trans women during cross-sex hormonal therapy: a prospective observational study.
Osteoporos Int 26:35-47.
Relation of adrenal steroids with bone maturation,-mineral density and -geometry in healthy prepubertal and early pubertal boys.
Bone 69:39-46.
Sex steroids in relation to sexual and skeletal maturation in obese male adolescents.
J Clin Endocrinol Metab 99:2977-85.
Associations of sex steroids with bone maturation, bone mineral density, bone geometry and body composition: a cross-sectional study in healthy male adolescents.
J Clin Endocrinol Metab Mar 99:E1272-82.
Androgen receptor polymorphisms determines steroid concentrations, anthropometrics, but not muscle mass in young men.
Plos One 23;9(1).
Low bone mass is prevalent in male-to-female transsexual persons before start of cross-sex hormonal therapy and gonadectomy.
Bone 54:92-7.
Serum sclerostin levels in men with idiopathic osteoporosis.
Eur J Endocrinol 15:168:615-620.
Bone size and bone strength are increased in obese male adolescents.
J Clin Endocrinol Metab 98:3019-28.
Sunlight is an important determinant of vitamin D serum concentrations in cystic fibrosis.
Eur J Clin Nutr (65) 574-9.
Estrogen-specific action on bone geometry and volumetric bone density: longitudinal observations in an adult with complete androgen insensitivity.
Bone (45) 392-7.
Vitamin D binding protein, a new nutritional marker in cystic fibrosis patients.
Clin Chem Lab Med (46) 365-70.
Cholecalciferol and 25-hydroxyvitamin D concentrations in adults with cystic fibrosis.
Am J Clin Nutr 87 (1) 190.
Prediction of Glucose Intolerance in Early Postpartum in Women with Gestational Diabetes Mellitus Based on the 2013 WHO Criteria.
J Clin Med. 2019 Mar 19;8(3). pii: E383. doi: 10.3390/jcm8030383.
Risk factor screening for gestational diabetes mellitus based on the 2013 WHO criteria.
Eur J Endocrinol. 2019 Jun 1;180(6):353-363. doi: 10.1530/EJE-19-0117. PMID: 31120231
Characteristics and pregnancy outcomes across gestational diabetes mellitus subtypes based on insulin resistance.
Diabetologia. 2019 Nov;62(11):2118-2128. doi: 10.1007/s00125-019-4961-7. Epub 2019 Jul 23. PMID: 31338546
Adrenal insufficiency, be aware of drug interactions!
Endocrinol Diabetes Metab Case Rep. 2019 Oct 3;2019. pii: EDM190062. doi: 10.1530/EDM-19-0062. PMID: 31581123 Free PMC Article
Textiloma-Induced 1,25-Dihydroxyvitamin D-Mediated Hypercalcemia: A Case Report and Literature Study.
J Endocr Soc. 2019 Aug 27;3(11):2158-2164. doi: 10.1210/js.2019-00206. eCollection 2019 Nov 1. PMID: 31687642 Free PMC Article
A Modified Two-Step Screening Strategy for Gestational Diabetes Mellitus Based on the 2013 WHO Criteria by Combining the Glucose Challenge Test and Clinical Risk Factors.
J Clin Med. 2018 Oct 13;7(10). pii: E351. doi: 10.3390/jcm7100351. PMID: 30322138
Evolution in the management of thyroid cancer: an observational study in two referral centres in Belgium.
Acta Clin Belg. 2018 Aug;73(4):287-291. doi: 10.1080/17843286.2018.1435478. Epub 2018 Feb 12. PMID: 29431057
The Sensitivity and Specificity of the Glucose Challenge Test in a Universal Two-Step Screening Strategy for Gestational Diabetes Mellitus Using the 2013 World Health Organization Criteria.
Diabetes Care. 2018 Jul;41(7):e111-e112. doi: 10.2337/dc18-0556. Epub 2018 May 10. No abstract available. PMID: 29748432
“White Thyroid” on Unenhanced Computed Tomography in Amiodarone-Induced Thyrotoxicosis Type 2.
Thyroid. 2018 Jun;28(6):769-772. doi: 10.1089/thy.2017.0651. Epub 2018 May 11. PMID: 29631498
Effect of Sitagliptin on Cardiovascular Outcomes in type 2 Diabetes.
N Engl J Med. 2015 Jul 16;373(3):232-42.doi: 10.1056/NEJMoa1501352. Erratum in:N Engl J Med. 2015 Aug
Bone scan alterations in aromatase inhibitor-treated patients.
Clin Nuci Med. 2015 Jan;40(1):38-40.doi:10.1097/RLU.0000000000000588.
Transaxillary robotic thyroidectomy: Belgian team learning from the first 50 cases.
B-ENT 2015; Suppl 24:61-8