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Behandeling op maat voor acute myeloïde leukemie
Acute myeloïde leukemie – AML – is de meest voorkomende vorm van acute leukemie bij volwassenen (incidentie: 2 tot 3 per 100.000 personen). De incidentie stijgt met de leeftijd, waardoor AML hoofdzakelijk een aandoening is van de oudere patiënt. De behandeling wordt bepaald door de leeftijdscategorie, de comorbiditeit en het cytogenetisch-moleculair onderzoek.
Efficacy of ruxolitinib in B-lymphoblastic leukaemia with PCM1-JAK2 fusion gene.
Br J Haematol. 2021 Feb;192(4):e112-e115. doi: 10.1111/bjh.17340. Epub 2021 Jan 27
Randomized phase 2 trial of pevonedistat plus azacitidine versus azacitidine for higher-risk MDS/CMML or low-blast AML.
Leukemia. 2021 Jul;35(7):2119-2124. doi: 10.1038/s41375-021-01125-4. Epub 2021 Jan 22. PMID: 33483617 Free PMC article. Clinical Trial. No abstract available.
Efficacy of ruxolitinib in B-lymphoblastic leukaemia with the PCM1-JAK2 fusion gene.
Br J Haematol. 2021 Feb;192(4):e112-e115. doi: 10.1111/bjh.17340. Epub 2021 Jan 27. PMID: 33502001 No abstract available.
Primary immune thrombocytopenia in adults: Belgian recommendations for diagnosis and treatment anno 2021 made by the Belgian Hematology Society.
Acta Clin Belg. 2021 Feb 26:1-14. doi: 10.1080/17843286.2021.1876310. Online ahead of print. PMID: 33635747
Oral Azacitidine Maintenance Therapy for Acute Myeloid Leukemia in First Remission.
N Engl J Med. 2020 Dec 24;383(26):2526-2537. doi: 10.1056/NEJMoa2004444. PMID: 33369355 Clinical Trial.
Effectiveness and Safety of Romiplostim Among Patients with Newly Diagnosed, Persistent and Chronic Immune Thrombocytopenia in European Clinical Practice.
Adv Ther. 2021 May;38(5):2673-2688. doi: 10.1007/s12325-021-01727-5. Epub 2021 Apr 18. PMID: 33866516 Free PMC article.
Clinical outcomes in patients with Philadelphia chromosome-positive leukemia treated with ponatinib in routine clinical practice-data from a Belgian registry.
Ann Hematol. 2021 Jul;100(7):1723-1732. doi: 10.1007/s00277-021-04507-x. Epub 2021 May 4. PMID: 33942128 Free PMC article.
A phase 2a randomized clinical trial of intravenous vedolizumab for the treatment of steroid-refractory intestinal acute graft-versus-host disease.
Bone Marrow Transplant. 2021 Oct;56(10):2477-2488. doi: 10.1038/s41409-021-01356-0. Epub 2021 Jun 9. PMID: 34108672 Free PMC article. Clinical Trial.
Management of adverse events in patients with acute myeloid leukemia in remission receiving oral azacitidine: experience from the phase 3 randomized QUAZAR AML-001 trial.
J Hematol Oncol. 2021 Aug 28;14(1):133. doi: 10.1186/s13045-021-01142-x. PMID: 34454540 Free PMC article. Clinical Trial.
Oral azacitidine preserves favorable level of fatigue and health-related quality of life for patients with acute myeloid leukemia in remission: results from the phase 3, placebo-controlled QUAZAR AML-001 trial.
Haematologica. 2021 Sep 23. doi: 10.3324/haematol.2021.279174. Online ahead of print. PMID: 34551506 Free article.
Sequential administration of low dose 5-azacytidine (AZA) and donor lymphocyte infusion (DLI) for patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) in relapse after allogeneic stem cell transplantation (SCT): a prospective study from the Belgian Hematology Society (BHS).
Bone Marrow Transplant. 2021 Oct 5. doi: 10.1038/s41409-021-01464-x. Online ahead of print. PMID: 34611291 No abstract available.
Acute thyrotoxicosis after SCT.
Bone Marrow Transplant. 2009 Apr;43(8):663-4. Epub 2008 Nov 17. No abstract available. PMID: 19011663 [PubMed - indexed for MEDLINE] PMID: 17986280
Targeted next generation DNA sequencing for the detection of clonal haematopoiesis in idiopathic cytopaenia of undetermined significance (ICUS).
Belgian Journal of Hematology 2019;10:231-40
Targeted next generation DNA sequencing for the detection of clonal haematopoiesis in idiopathic cytopaenia of undetermined significance (ICUS).
Belgian Journal of Hematology 2019;10:231-40
Targeted next generation DNA sequencing for the detection of clonal haematopoiesis in idiopathic cytopaenia of undetermined significance (ICUS).
BELG J HAEMATOL 2019;10(6):231-40
Mediastinal Myeloid Sarcoma with TP53 Mutation Preceding Acute Myeloid Leukemia with a PICALM-MLLT10 Fusion.
Acta Haematol 2018;140:97–104
“A disseminated Mycoplasma hominis infection in a patient with an underlying defect in humoral immunity”.
Infection. 44(3):379-81.
Clinical challenges and images in GI. Fasciola hepatica infection and Von Hippel-Lindau disease type 1 with pancreatic and renal involvement.
Gastroenterology 2007;132:15-6, 467-8.
Clinical challenges and images in GI. Fasciola hepatica infection and Von Hippel-Lindau disease type 1 with pancreatic and renal involvement.
Gastroenterology 2007;132:15-6, 467-8.
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