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laboratorium geneeskunde

De dienst Laboratoriumgeneeskunde gaat voor ‘samen sterker’

Campus Sint-Jan en campus Henri Serruys houden er voortaan één gemeenschappelijke dienst Laboratoriumgeneeskunde op na. Een fusie die de dienstverlening…

Lipoproteïnen van verschillende grootte en densiteit gescheiden na ultracentrifugatie

Dienst Laboratoriumgeneeskunde voortrekker in Europees cardiovasculair preventiebeleid

Op 25 en 26 september 2014 organiseerden de European Atherosclerosis Society (EAS) en de European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) hun eerste gemeenschappelijke symposium in het concertgebouw van Brugge, de “Atherosclerosis and Cardio-Endocrine Biomarkers Course”. Prof. dr. Michel Langlois trad op als voorzitter namens de Belgian Lipid Club en de dienst Laboratoriumgeneeskunde van het AZ Sint-Jan Brugge-Oostende AV. Internationale opinieleiders gaven er – voor een multidisciplinair publiek van endocrinologen, cardiologen, huisartsen, klinisch biologen en laboratoriumtechnologen – hun visie over nieuwe biomerkers voor het management van dyslipidemie en de preventie van atherosclerose en cardiovasculaire ziekte. Hierna volgt een verslag van enkele relevante presentaties voor de klinische praktijk.
Karotype Trisomie

Evolutie van de prenatale screening naar aneuploïdie in het eerste trimester: van leeftijd tot NIPT

Twee à vier procent van alle pasgeborenen heeft een min of meer ernstige aangeboren misvorming. De huidige prenatale diagnostiek probeert…

Nieuwe laboratorium­benaderingen voor de preventie van cardiovasculaire morbiditeit en mortaliteit

Op 20 oktober 2007 vond in Brugge het Symposium van de Belgian Lipid Club (BLC) plaats, georganiseerd door dr. M. Langlois van het Laboratorium Klinische Scheikunde van AZ Sint­Jan AV en Prof. V. Blaton. Naast enkele toonaangevende opinieleiders (Prof. P. Lansberg en Prof. J. Kastelein van het departement Vasculaire Geneeskunde van de Universiteit Amsterdam, Prof. G. De Backer van de Universiteit Gent en Prof. L. Van Gaal van de Universiteit Antwerpen) gaven zij er een presentatie over nieuwe benaderingenvoor de preventie van cardiovasculaire morbiditeit en mortaliteit.

Bone scan alterations in aromatase inhibitor-treated patients.

Clin Nucl Med. 2015 Jan;40(1):38-40. doi: 10.1097/RLU.0000000000000588. PMID: 25290288

Spuriously high thyrotropin values due to anti-thyrotropin antibodies in adult patients.

Clin Chem Lab Med. 2009;47(5):604-6. PMID: 19397486

The CCA Special Issue on Cardiovascular Markers.

Clin Chim Acta. 2020 [Editorial] doi: 10.1016/j.cca.2020.10.036

Update on current practice in laboratory medicine in respect of natriuretic peptide testing for heart failure diagnosis and management in Europe.

The CARdiac MArker Guideline Uptake in Europe (CARMAGUE) study. Clin Chim Acta 2020;511:59-66.

How well do laboratories adhere to recommended guidelines for dyslipidaemia management in Europe?

The CArdiac MARker Guideline Uptake in Europe (CAMARGUE) study. Chim Acta. 2020;508:267-272.

Non-HDL Cholesterol or apoB: Which to Prefer as a Target for the Prevention of Atherosclerotic Cardiovascular Disease?

Curr Cardiol Rep. 2020;22:67.

Quantifying atherogenic lipoproteins for lipid-lowering strategies: consensus-based recommendations from EAS and EFLM.

Atherosclerosis 2020;294:46-61.

Quantifying atherogenic lipoproteins for lipid-lowering strategies: consensus-based recommendations from EAS and EFLM.

Clin Chem Lab Med. 2020;58:496-517.

Evolving concepts on the management of dyslipidaemia.

Acta Clin Belg – Int J Clin Lab Med 2020;75:80-90.

Investigations on the clinical utility of apolipoprotein B measurement: A research priority.

Eur J Prev Cardiol. 2020;27:1252–1254 [Editorial].

Muscle strength is a major determinant of the blood pressure response to isometric stress testing: the Asklepios population study.

J Hypertens 2020;38:224-234.

Quantifying atherogenic lipoproteins for lipid-lowering strategies: consensus-based recommendations from EAS and EFLM.

Atherosclerosis 2020 doi: 10.1016/j.atherosclerosis.2019.12.005.

Quantifying atherogenic lipoproteins for lipid-lowering strategies: consensus-based recommendations from EAS and EFLM.

Clin Chem Lab Med. 2019 doi: 10.1515/cclm-2019-1253.

Evolving concepts on the management of dyslipidaemia.

Acta Clin Belg – Int J Clin Lab Med 2019 https://doi.org/10.1080/17843286.2019.1702823

Muscle strength is a major determinant of the blood pressure response to isometric stress testing: the Asklepios population study.

J Hypertens 2020;38:224-234.

Investigations on the clinical utility of apolipoprotein B measurement: A research priority.

Eur J Prev Cardiol. 2019 doi: 10.1177/2047487319869578

Evaluation of four hemoglobin separation analyzers for hemoglobinopathy diagnosis.

J Clin Lab Anal. 2018;32:e22224.

Leukocyte telomere length and diet in the apparently healthy, middle-aged Asklepios population.

Sci Rep. 2018;8:6540.

Quantifying Atherogenic Lipoproteins: Current and Future Challenges in the Era of Personalized Medicine and Very Low Concentrations of LDL Cholesterol. A Consensus Statement from EAS and EFLM.

Clin Chem. 2018;64:1006-1033.

The Role of Nutraceuticals in Statin Intolerant Patients.

J Am Coll Cardiol. 2018;72:96-118.

Which Lipids Should Be Analyzed for Diagnostic Workup and Follow-up of Patients with Hyperlipidemias?

Curr Cardiol Rep. 2018;20:88.

Overview of the current status of familial hypercholesterolaemia care in over 60 countries – The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC).

Atherosclerosis. 2018;277:234-255.

A Belgian consensus strategy to identify familial hypercholesterolaemia in the coronary care unit and its subsequent cascade screening and treatment: BEL-FaHST (The BELgium Familial Hypercholesterolaemia STrategy).

Atherosclerosis. 2018;277:369-376.

Evaluation of Four Hemoglobin Separation Analyzers for Hemoglobinopathy Diagnosis.

Journal of Clinical Lab Analysis 2018;32(1)

First EAS – EFLM consensus guideline on non-fasting lipid testing and reporting.

IFCC e-newsletter May-June 2016;20-21.

Lipidentesten op niet-nuchtere bloedafnames.

Eur Heart J 2016 en Clin Chem 2016 namens de Europese EAS/EFLM expertgroep

“Lipiden en lipoproteïnen” In: Wegwijs in Laboratoriumdiagnose.

Uitgeverij Acco 2016 p. 273-92. ISBN 978-94-6292-305-8.

Why are clinical practice guidelines not followed?

Clin Chem Lab Med. 2016;54:1133-9.

Haptoglobin phenotype and Parkinson disease risk.

Parkinsonism Relat Disord. 2016;22:108-9.

Fasting is not routinely required for determination of a lipid profile-a joint consensus statement from the European Atherosclerosis Society and European Federation of Clinical Chemistry and Laboratory Medicine.

Eur Heart J. 2016;37:1944-58

How Well Do Laboratories Adhere to Recommended Clinical Guidelines for the Management of Myocardial Infarction: The CARdiac MArker Guidelines Uptake in Europe Study (CARMAGUE).

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Clin Chem. 2016;62:1264-71.

Could accreditation bodies facilitate the implementation of medical guidelines in laboratories?

Clin Chem Lab Med. 2016 [Epub ahead of print]

Bone scan alterations in aromatase inhibitor-treated patients.

Clin Nuci Med. 2015 Jan;40(1):38-40.doi:10.1097/RLU.0000000000000588.

HDL-gerichte therapieën: behandeling van een risicofactor of make-up van een risicomerker?

ISBN 978-90-81054-26-3 Transmed Medical Communications 2013 pp. 29-46.

Serum amyloid A is independently related to apolipoprotein A-I but not to HDL-cholesterol in patients with angina pectoris Clin Biochem.

2013 [Epub ahead of print].

Genetic aspects of scurvy and the European famine of 1845-1848

Nutrients 2013; 5:3582-8.

Comparison of two immunoassays for measurement of faecal calprotectin in detection of Inflammatory Bowel Disease: (pre)-analytical and diagnostic performance characteristics.

Clin Chem Lab Med 2013 (in press).

Guideline from the European Atherosclerosis Society: clinical view on laboratory checklist and issues

Biochimica clinica 2013; 375(Suppl.):S36

Critical review of laboratory investigations in clinical practice guidelines: proposals for the description of investigation.

Clin Chem Lab Med. 2013; 51:1217-26.

Pseudonephritis is Associated With High Urinary Osmolality and High Specific Gravity in Adolescent Soccer Players.

Pediatr Exerc Sci. 2013; 25:360-9

Accuracy of three automated 25-hydroxyvitamin D assays in haemodialysis patients

Clin Chim Acta 2013; 415:255-60

Is it time to apply genographics in medical diagnosis?

Acta Clin Belgica 2012;67:387-8.

Human plasma protein polymorphisms and the persistence of cultural diversity.

Proc Natl Acad Sci U S A. 2012;109(43):E2914.

How I treat dyslipidemia according to the cardiovascular risk profile?

Rev Med Liège 2012; 67:167-173.

A genome-wide association study identifies rs2000999 as a strong genetic determinant of circulating haptoglobin levels

PLoS ONE 2012;7:e32327

Postanalytical opportunities of lipid and lipoprotein testing:laboratory approaches for predicting and managing risk of cardiovascular disease

Clin Chem Lab Med (invited article) 2012; 50:1169–1181.

The haptoglobin phenotype influences the risk of cutaneous squamous cell carcinoma in kidney transplant patients

J Eur Acad Dermatol Venereol 2012; 26:566-71.

CASE REPORT: SPURIOUSLY HIGH VITAMIN A AND E LEVELS DUE TO HYPERLIPIDEMIA.

26/10/2020
Virtual RBSLM Annual Meeting (Royal Belgian Society of Laboratory Medicine)

Lipid testing in 2020.

04/06/2020
Webinar CCA (Clin Chim Acta)

Update on Dyslipidaemia Guidelines and the rationale of Cardiovascular Disease Biomarker.

23/05/2019
Barcelona

“Dyslipidemia- New clinical concepts and diagnostic tools”

23/09/2016
Warschau

Evaluation of Four Hemoglobin A1c Instruments.

21-24/09/2016
Warschau

“Non-fasting lipid profiles: implications for lipoprotein measurement and reporting”

07/06/2016
EFLM e-seminar

“Haptoglobin genotype and risk markers of cardiovascular disease”

27/09/2013
Denemarken

LOK Cardiologie Richtlijnen en valkuilen bij het management van dyslipidemie

09/09/2013
Brugge

Euromedlab IFCC-EFLM Congress

22/05/2013
Milaan

Comparison of two extraction devices for determination of faecal calprotectin on ImmunoCAP250

19/05/2013
Milaan

Serum amyloid A is independently related to apolipoprotein A-I but not to HDL-cholesterol in patients with angina pectoris

19/05/2013
Milaan

Accuracy of three automated 25-hydroxyvitamin D immunoassays compared to ID-XLC-MSMS in haemodialysis patients

19/05/2013
Milaan

Accuracy of three automated immunoassays compared to ID-XLC-MSMS for the measurement of 25-hydroxyvitamin D in haemodialysis patients

20/10/2012
Gent

16éme Journée de Biologie Clinique

12/05/2012
Brussel

EliA™ CTD screen: enzyme fluoroimmunoassay for ANA detection

Symposium KBVKC, EAS Guidelines for dyslipidemia management

03/05/2012
Groot-Bijgaarden
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